Hair Loss Forum - Cotsarelis: We are not performing any clinical trials at this time.
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Iron_Man

24.03.2012, 07:17
 

Cotsarelis: We are not performing any clinical trials at this time. (Hair Multiplication & Stem Cells Treatment)

http://www.uphs.upenn.edu/news/News_Releases/2012/03/hair/

A Note to Individuals Interested in Treatments Based on this Research

From George Cotsarelis:
Thank you for your interest in our research. If you have hair loss, we recommend seeing a dermatologist, as there are other causes of hair loss and some treatments currently available.

We are not performing any clinical trials at this time. The findings from this study have not yet led to any clinical trials. Please refer to the National Institutes of Health clinical trial site clinicaltrials.gov for ongoing hair loss studies.

This research would not have been possible without public and private grants. If you would like support biomedical research directly, please consider supporting Penn's Dermatology research.

Video:
http://bcove.me/667afmz6
<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<<

Seems they got bombarded with emails from psy...s.
Anyway, at least Cots got through the press what he wanted - attention.




Iron_Man is located in [NA] and he is available to meet: NO

---
I documented the world’s 1st day-by-day (HST) donor hair regeneration process …


Post reply
Iron_Man

24.03.2012, 07:32

@ Iron_Man

Cotsarelis: We are not performing any clinical trials at this time.

http://www.uphs.upenn.edu/news/News_Releases/2012/03/hair/
[image]
Pic above: "Miniaturized human hair follicle shows concentration of Prostaglandin D2 (in green). Credit: Garza and Cotsarelis/Penn Medicine"

Read more about miniaturized/dead follicles...
http://www.hairsite.com/hair-loss/board_entry-id-98959.html#p98977




Iron_Man is located in [NA] and he is available to meet: NO

---
I documented the world’s 1st day-by-day (HST) donor hair regeneration process …


Post reply
jimmy

24.03.2012, 08:20

@ Iron_Man

Cotsarelis: We are not performing any clinical trials at this time.

Iron_Man, you're obviously a hugely knowledgeable guy about hairloss, and your various arguments for why proposed solutions won't work always seem convincing; I'm curious, aside from gho, do you see a solution ever coming to market? If so, what kind of 'cure' do you envisage?




jimmy is located in [NA] and he is available to meet: NO


Post reply
Iron_Man

24.03.2012, 12:29

@ jimmy

Cotsarelis: We are not performing any clinical trials at this time.

» ... do you see a solution ever coming
» to market? If so, what kind of 'cure' do you envisage?

I think that depends on whether you understand the following:

Let’s assume your own normal human body, including everything (blood, nerves, muscles, brain, organs etc etc etc), is initially completely normal and healthy -but your WHOLE skeleton is the main cause for your progressing illness, because your whole SKELETON has a malignant disease (genetic defect, bone cancer, whatever) – so how to REPLACE (e.g. skeleton from a “healthy” and genetically compatible cadaver) your whole skeleton?

If you find a solution – let me know, and hair loss is cured.

Because concerning hair follicles – the same problem; I have “just” to replace their sick skeleton(s) with healthy and native skeletons and everything will be normal again: you will get normal cycling terminal hairs again and I will get the nobel prize.

If you find the example above funny – unfortunately, it’s not:
[image]
(pic from Cotsarelis' recent study)
It’s the hair follicles’ “skeletons” which basically –in full awareness due to its nature- who produces this or that or tells his "subordinates" to produce OR to destroy this or that – in addition, sometimes in cooperation with other institutions, like ‘hormones’.

Below, for example, the pic shows such a “skeleton” under a microscope...
[image]
...and the problem is that every single “skeleton” is build to have its own characteristic (produces its own proteins etc), instructions and programming. Furthermore, just one “simple” hair follicle consists of several different skeletons (I'm NOT talking about cells!), whereby every single skeleton has its own instructions (works “site-specific”) and so on.

So how to cure all these different skeletons (to cure them, NO WAY! – at least not within the coming 50 years or so, if at all) or how to replace (and with what exactly) all these different, native and site-specific skeletons? All this is the reason, why there is still no real cure for e.g. cancer.

So the question is,
what kind of 'cure' do YOU envisage in awareness of all this?




Iron_Man is located in [NA] and he is available to meet: NO

---
I documented the world’s 1st day-by-day (HST) donor hair regeneration process …


Post reply
2020

24.03.2012, 15:53

@ Iron_Man

Cotsarelis: We are not performing any clinical trials at this time.

» » ... do you see a solution ever coming
» » to market? If so, what kind of 'cure' do you envisage?
»
» I think that depends on whether you understand the following:
»
» Let’s assume your own normal human body, including everything (blood,
» nerves, muscles, brain, organs etc etc etc), is initially completely normal
» and healthy -but your WHOLE skeleton is the main cause for your progressing
» illness, because your whole SKELETON has a malignant disease (genetic
» defect, bone cancer, whatever) – so how to REPLACE (e.g. skeleton from a
» “healthy” and genetically compatible cadaver) your whole skeleton?
»
» If you find a solution – let me know, and hair loss is cured.
»
» Because concerning hair follicles – the same problem; I have “just” to
» replace their sick skeleton(s) with healthy and native skeletons and
» everything will be normal again: you will get normal cycling terminal hairs
» again and I will get the nobel prize.
»
» If you find the example above funny – unfortunately, it’s not:
» [image]
» (pic from Cotsarelis' recent study)
» It’s the hair follicles’ “skeletons” which basically –in full awareness due
» to its nature- who produces this or that or tells his "subordinates" to
» produce OR to destroy this or that – in addition, sometimes in cooperation
» with other institutions, like ‘hormones’.
»
» Below, for example, the pic shows such a “skeleton” under a microscope...
» [image]
» ...and the problem is that every single “skeleton” is build to have its own
» characteristic (produces its own proteins etc), instructions and
» programming. Furthermore, just one “simple” hair follicle consists of
» several different skeletons (I'm NOT talking about cells!), whereby every
» single skeleton has its own instructions (works “site-specific”) and so
» on.
»
» So how to cure all these different skeletons (to cure them, NO WAY! – at
» least not within the coming 50 years or so, if at all) or how to replace
» (and with what exactly) all these different, native and site-specific
» skeletons? All this is the reason, why there is still no real cure for
» e.g. cancer.
»
» So the question is,
» what kind of 'cure' do YOU envisage in awareness of all this?


then explain to me how replicel histogen and aderans have already been able to grow hair?




2020 is located in [NA] and he is available to meet: NO


Post reply
Iron_Man

24.03.2012, 18:58

@ 2020

Cotsarelis: We are not performing any clinical trials at this time.

» then explain to me how replicel histogen and aderans have already been able
» to grow hair?

Did they?

G. Cotsarelis (Follica) and K. Stenn (Aderans) 2007…
>>>>>>>>>>>>
“With the advent of stem cell biology, we anticipate that many attempts to engineer hair follicles will be made in the near future. The epidermal stem cells or progenitor cells may derive from many sources:
embryonic stem cells, engineered embryonic stem cells or cell lines, interfollicular epidermal stem cells, bulge stem cells, or even bone marrow stem cells. Because the cells may have different competences, the “hair follicles” built with them may be different.”

<<<<<<<<<<<<<<<<

So the question is - what type/kind exactly of “hair follicle” did all these companies you mention built so far?

“Real” and normal cycling thick terminal hairs producing follicles?
Chimeric/hybrid hair follicles?
Just “Hair follicle–like” structures?
Rather “tumor-like”follicles”?
Nothing in humans with the same procedure they used in animals?

And now explain to ME - what could you see so far?

For example,
what type/kind of hairs exactly build the Replicel guys with completely the same cells types and procedure in 1) mouse footpad and 2) mouse ear?
What’s the reason for the different results?




Iron_Man is located in [NA] and he is available to meet: NO

---
I documented the world’s 1st day-by-day (HST) donor hair regeneration process …


Post reply
jarjarbinx

24.03.2012, 23:53

@ Iron_Man

I was right, Follica has jumped the shark

We now know that Follica does not have any treatment in any clinical trials. I was right. Follica has jumped the shark.




jarjarbinx is located in [NA] and he is available to meet: NO


Post reply
cal

25.03.2012, 02:23

@ jarjarbinx

I was right, Follica has jumped the shark

» We now know that Follica does not have any treatment in any clinical
» trials. I was right. Follica has jumped the shark.

And this new knowledge of failure is based on . . . what?

Up to now we have not known either way. It's purely your opinion that no news from them equals failure.




cal is located in [NA] and he is available to meet: NO


Post reply
crashul

25.03.2012, 10:27

@ jarjarbinx

I was right, Follica has jumped the shark

» We now know that Follica does not have any treatment in any clinical
» trials. I was right. Follica has jumped the shark.

"We are not performing any clinical trials at this time." The guy said that on behalf of Penn Medicine which is mostly a government financed institution.

Follica is a private company. That statement was not made on behalf of Follica.




crashul is located in [NA] and he is available to meet: NO


Post reply
KO

25.03.2012, 12:22

@ crashul

I was right, Follica has jumped the shark

» » We now know that Follica does not have any treatment in any clinical
» » trials. I was right. Follica has jumped the shark.
»
» "We are not performing any clinical trials at this
» time." The guy said that on behalf of Penn Medicine which is mostly
» a government financed institution.
»
» Follica is a private company. That statement was not made on behalf of
» Follica.

Even Follica is not performing a clinical trial right now. They have finished P2. and not started P3.


But that doesn't stop jarjar from being jarjar.


At least he's backed off the incorrect 73% growth number.




KO is located in [NA] and he is available to meet: NO


Post reply
jarjarbinx

25.03.2012, 12:30

@ KO

I was right, Follica has jumped the shark

» » » We now know that Follica does not have any treatment in any clinical
» » » trials. I was right. Follica has jumped the shark.
» »
» » "We are not performing any clinical trials at this
» » time." The guy said that on behalf of Penn Medicine which is
» mostly
» » a government financed institution.
» »
» » Follica is a private company. That statement was not made on behalf of
» » Follica.
»
» Even Follica is not performing a clinical trial right now. They have
» finished P2. and not started P3.
»
»
» But that doesn't stop jarjar from being jarjar.
»
»
» At least he's backed off the incorrect 73% growth number.


I hven't backed of anything. I'm tired of saying the same thing over and over again to person who simply doesn't get it. I told you it's 73%, it is 73%, that is that, you can say whatever contrare poo you want to, but I am not saying anything else about it.




jarjarbinx is located in [NA] and he is available to meet: NO


Post reply
KO

25.03.2012, 14:25

@ jarjarbinx

I was right, Follica has jumped the shark

»
»
» I hven't backed of anything. I'm tired of saying the same thing over and
» over again to person who simply doesn't get it. I told you it's 73%, it is
» 73%, that is that, you can say whatever contrare poo you want to, but I am
» not saying anything else about it.

Histogen did not show 73% growth in their trial results. According to their published paper it was much closer to 20%. Why is it so difficult for you to grasp that?




KO is located in [NA] and he is available to meet: NO


Post reply
moawk

Germany,
25.03.2012, 15:39

@ jarjarbinx

I was right, Follica has jumped the shark

» » » » We now know that Follica does not have any treatment in any clinical
» » » » trials. I was right. Follica has jumped the shark.
» » »
» » » "We are not performing any clinical trials at this
» » » time." The guy said that on behalf of Penn Medicine which is
» » mostly
» » » a government financed institution.
» » »
» » » Follica is a private company. That statement was not made on behalf of
» » » Follica.
» »
» » Even Follica is not performing a clinical trial right now. They have
» » finished P2. and not started P3.
» »
» »
» » But that doesn't stop jarjar from being jarjar.
» »
» »
» » At least he's backed off the incorrect 73% growth number.
»
»
» I hven't backed of anything. I'm tired of saying the same thing over and
» over again to person who simply doesn't get it. I told you it's 73%, it is
» 73%, that is that, you can say whatever contrare poo you want to, but I am
» not saying anything else about it.


I think you need to jump the shark.
Do you really have that much faith in histogen?




moawk is located in GERMANY and he is available to meet: NO

---
1. Predicted the failure of replicel, months in advance.
2. Predicted how their stock would rise/drop even with exact numbers.
3. Predicted the wild claims and crazyness that gc83uk's donor regeneration will cause among the HT industry during this summer. Including rassman's opinion, Dr. Woods special patients and Pro hair clinic photos.
4. Predicted Gho will open up a clinic in asia.
5. No prediction on Histogen. Looks promising if they didn't fake results.
6. Predicted the only viable HM technique other than Gho would surface when hairs are: "generated through the appropriate cell populations" -Team Tokyo 2012


[image]
- Moawk

Advice for patients: If you are considering a hair transplant, only consider Gho's HST and nothing else. First HT treatment in the world that offers: zero scarring, small downtime and donor regrowth.
http://www.hasci.com

Advice for Investors in HM: Invest in Team Tokyo.
http://www.tsuji-lab.com/en/research/organ/hair.html
Ditch replicel, aderans. They are done for and have no future.


Post reply
MikadoMan

25.03.2012, 15:49

@ KO

Follice or research didnt jump the shark

Hi i registered here because of IM.

there are some things IM fails to adress and with strange intentions

he comes up with this whole no cure in 50 years stuff to drive people into suicide or into stressful times to put them down because he is old

the whole skeleton analogy has one big flaw, he says no cure because they are all different. but why does finasterid and minox work in general?

now IMs new scheme is the whole go to Cotsarelis and use his pictures, isnt it strange that IM always jumps on new things which he ignored totally before hand.

follicles on your head take in general a ver long time to really die and this balding process is very different, there are men with the age of 70 who have a nw7 pattern but vellus hairs on their head after closer inspection

why can´t IM give straight answers instead of the use of riddles and such, this shows clearly that all in all he simply doesnt know anything at all and he is also speculating

even the small numbers of regrowth in th histogen and replicel cases show his theory as invalid.

also if all hairs are totally individual skeletons then ghos hst wouldnt work constantly

only because he has finally accept his fate he wants to turn other people into depression.

also you can see this in this users gcuk thread about his gho experience, IM firstly played the all knowing gho guy but then he asked gcuk a lot of question where he would have called others psychos and losers for. a very strange guy

so in other words he doesnt know anything even if he wants people to make believe it, thats the reason why he always give away vague statements instead of definite answers.

facts are that ou can and could cure hair loss and reverse it because there is a dominance to certain cells, thats the reason why donor harvested follicles can survive in recipient sides. because otherwise it simply wouldnt work at all

also all those micro steps are adding up from month to month and we all know what IM said a few months ago

"replicel has a unique and plausible thing" or something along the lines.

when i recall his history from reading here its quiet obvious to me why he does this, its one simple thing

"all approaches here need one thing in common : - healthy dormant or minituarized follicles and/or healthy skin to work with"

if you had micro surgery done on your head, you destroyed the whole constitution of your head and therefore you destroyed follicles.

yes you can create follicles from the scratch but they also need healthy starting conditions and thats not given on a transplanted head. on massive traumatized scar tissue, you simply cannot force follicles to grow at all. thats the reason why all reasearchers will ignore questions like

"will this work on transplanted areas done by FUT/FUE"

also all those current pieces are not pieces from the beginning, those are final pieces and one poster here roger that really got it correct.

i study bio science and i can tell that hair loss is much less difficult to reverse then cancer for example, cancer is difficult because you cant predict patterns of cancer while even different, hair loss can be predicted to a high degree.

and there is also one minor thing especially IM fails to acknowledge, all those findings are actually based on results they saw with their eyes and so if you can reverse only one follicle to normal, then you can do it with all of them also and i think no one here would deny that in all those years, at least one hair had been rejuvenated etc.

i dont claim my statements to be the absolute truth like someone like IM would say, but i think i am at least very close to it




MikadoMan is located in [NA] and he is available to meet: NO

---
You wanna get all the answers why none of your "ethical" clinics have adopted Ghos HST hairmuliplication so far?

THEN READ THIS http://www.hairsite.com/hair-loss/img/uploaded_files/2879_file32.pdf


Post reply
appleguy

25.03.2012, 16:06

@ MikadoMan

Follice or research didnt jump the shark

Agreed and well said!

I am sick and tired of the naysayres saying similar things in reference to new findings.

The cancer thing was dumb and is so difficult to kill of because it mimics so closely a natural process just running out of control and has so many root causes, much less than MPB.

The fact is if MPB had had the amount of research as cancer it would have been cured decades ago.

I also agree it is sour grapes from post transplant patients who know this stuff wont work for them so they will do their best to tell everyone else it won't work period.

I also think that doctors who say ten years minimum for a cure would like that to be the case...
Where's the money to be made in research if some gobo comes up with a cure.




appleguy is located in [NA] and he is available to meet: NO


Post reply
KO

25.03.2012, 16:15

@ moawk

I was right, Follica has jumped the shark

No one else seems to think Histogen grew 73% more hair. The paper posted on their own website flatly said about 20%, which is in the league of minox/fin.




KO is located in [NA] and he is available to meet: NO


Post reply
MikadoMan

25.03.2012, 16:36

@ appleguy

Follice or research didnt jump the shark

» Agreed and well said!
»
» I am sick and tired of the naysayres saying similar things in reference to
» new findings.
»
» The cancer thing was dumb and is so difficult to kill of because it mimics
» so closely a natural process just running out of control and has so many
» root causes, much less than MPB.
»
» The fact is if MPB had had the amount of research as cancer it would have
» been cured decades ago.
»
» I also agree it is sour grapes from post transplant patients who know this
» stuff wont work for them so they will do their best to tell everyone else
» it won't work period.
»
» I also think that doctors who say ten years minimum for a cure would like
» that to be the case...
» Where's the money to be made in research if some gobo comes up with a cure.

Absolutely correct observations

you simply cant take naysayers seriously because they say the same things every time something new comes up

exactly cancer is working on many different levels and yes its mimicking natural processes thats the reason why its hard to diagnose and find cancer, while for example MPB leaves no room for speculations.

yes DHT is a hormone and not as complex as cancer, especially when you see that even Finasterid can prevent baldness from progressing and thats just a simple pill.

so even if iron man would be correct with his skeleton analogy, if you switch off the substance which attacks the skeleton you are done and for good.

of course its sour grapes from post op patients, and if you look closely all those naysayers are majority of FUT transplantation people who now seem to regret there approach.

unfortunately you are right with the whole research thing, hair loss is not considered important by science in contrast to cancer, the reason why right now more and more is done towards baldness is simply because they can make easy money with a not so deep research at all.

believe me its not as complex as iron man always want people to believe it is.

just to make it clear, in the 90s there were no real breakthroughs and no to very few research in regards of hair loss.

but if you take a look now, the moment some money was invested and research began, after lets say a decade, the results and findings were exponentially rising, even from those early reaearch ideas some other ideas spread across as well.

our problem is very simple, if they had this knowledge from today in the 80s or early 90s we would have a solution and also ghos transplantation technique as an unquestionable standard

and no it wont be ten years from now, it will be much lesser time, thats for sure




MikadoMan is located in [NA] and he is available to meet: NO

---
You wanna get all the answers why none of your "ethical" clinics have adopted Ghos HST hairmuliplication so far?

THEN READ THIS http://www.hairsite.com/hair-loss/img/uploaded_files/2879_file32.pdf


Post reply
moawk

Germany,
25.03.2012, 16:37

@ MikadoMan

Follice or research didnt jump the shark

» Hi i registered here because of IM.
»
» there are some things IM fails to adress and with strange intentions
»
» he comes up with this whole no cure in 50 years stuff to drive people into
» suicide or into stressful times to put them down because he is old
»
» the whole skeleton analogy has one big flaw, he says no cure because they
» are all different. but why does finasterid and minox work in general?
»
» now IMs new scheme is the whole go to Cotsarelis and use his pictures, isnt
» it strange that IM always jumps on new things which he ignored totally
» before hand.
»
» follicles on your head take in general a ver long time to really die and
» this balding process is very different, there are men with the age of 70
» who have a nw7 pattern but vellus hairs on their head after closer
» inspection
»
» why can´t IM give straight answers instead of the use of riddles and such,
» this shows clearly that all in all he simply doesnt know anything at all
» and he is also speculating
»
» even the small numbers of regrowth in th histogen and replicel cases show
» his theory as invalid.
»
» also if all hairs are totally individual skeletons then ghos hst wouldnt
» work constantly
»
» only because he has finally accept his fate he wants to turn other people
» into depression.
»
» also you can see this in this users gcuk thread about his gho experience,
» IM firstly played the all knowing gho guy but then he asked gcuk a lot of
» question where he would have called others psychos and losers for. a very
» strange guy
»
» so in other words he doesnt know anything even if he wants people to make
» believe it, thats the reason why he always give away vague statements
» instead of definite answers.
»
» facts are that ou can and could cure hair loss and reverse it because there
» is a dominance to certain cells, thats the reason why donor harvested
» follicles can survive in recipient sides. because otherwise it simply
» wouldnt work at all
»
» also all those micro steps are adding up from month to month and we all
» know what IM said a few months ago
»
» "replicel has a unique and plausible thing" or something along the lines.
»
» when i recall his history from reading here its quiet obvious to me why he
» does this, its one simple thing
»
» "all approaches here need one thing in common : - healthy dormant or
» minituarized follicles and/or healthy skin to work with"
»
» if you had micro surgery done on your head, you destroyed the whole
» constitution of your head and therefore you destroyed follicles.
»
» yes you can create follicles from the scratch but they also need healthy
» starting conditions and thats not given on a transplanted head. on massive
» traumatized scar tissue, you simply cannot force follicles to grow at all.
» thats the reason why all reasearchers will ignore questions like
»
» "will this work on transplanted areas done by FUT/FUE"
»
» also all those current pieces are not pieces from the beginning, those are
» final pieces and one poster here roger that really got it correct.
»
» i study bio science and i can tell that hair loss is much less difficult to
» reverse then cancer for example, cancer is difficult because you cant
» predict patterns of cancer while even different, hair loss can be predicted
» to a high degree.
»
» and there is also one minor thing especially IM fails to acknowledge, all
» those findings are actually based on results they saw with their eyes and
» so if you can reverse only one follicle to normal, then you can do it with
» all of them also and i think no one here would deny that in all those
» years, at least one hair had been rejuvenated etc.
»
» i dont claim my statements to be the absolute truth like someone like IM
» would say, but i think i am at least very close to it

Dude you need to understand when you are an old timer have seen so many companies promise so much and fail horribly you simply tune out and turn negative, once intercytex was out that was it for me...i dont buy this HM ..."new cycling follicles on bald plates"....i think it can be a better treatment but not a cure.




moawk is located in GERMANY and he is available to meet: NO

---
1. Predicted the failure of replicel, months in advance.
2. Predicted how their stock would rise/drop even with exact numbers.
3. Predicted the wild claims and crazyness that gc83uk's donor regeneration will cause among the HT industry during this summer. Including rassman's opinion, Dr. Woods special patients and Pro hair clinic photos.
4. Predicted Gho will open up a clinic in asia.
5. No prediction on Histogen. Looks promising if they didn't fake results.
6. Predicted the only viable HM technique other than Gho would surface when hairs are: "generated through the appropriate cell populations" -Team Tokyo 2012


[image]
- Moawk

Advice for patients: If you are considering a hair transplant, only consider Gho's HST and nothing else. First HT treatment in the world that offers: zero scarring, small downtime and donor regrowth.
http://www.hasci.com

Advice for Investors in HM: Invest in Team Tokyo.
http://www.tsuji-lab.com/en/research/organ/hair.html
Ditch replicel, aderans. They are done for and have no future.


Post reply
Freddie555

25.03.2012, 17:51

@ moawk

Follice or research didnt jump the shark

If the Replicel hype does not pan out, that's it for me.

I'm mentally preparing myself to live with hair loss for the rest of my life.




Freddie555 is located in [NA] and he is available to meet: NO

---
"When true Hair Multiplication comes, it will arise out of the East." - John The Revelator, Feb. 18, 2001


Post reply
Iron_Man

25.03.2012, 20:55

@ MikadoMan

roger_that's daemon is back!

» Hi i registered here because of IM.
[image]

roger_that - you daemon is back! :-D




Iron_Man is located in [NA] and he is available to meet: NO

---
I documented the world’s 1st day-by-day (HST) donor hair regeneration process …


Post reply
hairman2

26.03.2012, 10:46

@ jarjarbinx

I was right, Follica has jumped the shark

» We now know that Follica does not have any treatment in any clinical
» trials. I was right. Follica has jumped the shark.

haha, you outed yourself again as Stevie.Dee again with the "I was right." bullsh*t. Only that r-tard would go around parading himself like that.




hairman2 is located in [NA] and he is available to meet: NO


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