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Could someone please explain to me exactly what Gho has invented? (Hair Multiplication & Stem Cells Treatment)

posted by roger_that, MARYLAND, 10.04.2011, 22:41

I would not knock Histogen for they are moving forward with a purpose. One
set of low cost shots and even with the onslaught of DHT, hair counts kept
increasing for one year in the safety trials. Wait till they try higher
and more frequent dosages before judging anything. If they can give us
back even 15% of our hair and thicken it up, that's more than what Gho has
delivered over the past 10 years by far!

I think it's unrealistic to assume that Histogen will work as an injectible agent, much less be approved by the FDA anytime soon.

Histogen is a kind of cocktail of cellular growth factors, and it may have all kinds of adverse effects and side-effects, short-term and long-term, including potential cancer/tumor formation. The fact that Histogen is not a single compound, but a more complex brew containing a lot of agents that act at the cellular, and maybe at the DNA level, will make it very hard for the FDA to perform a quick review of this stuff. And that is assuming it ever gets to the FDA. That alone could take years. Then once it hits the FDA bureaucracy, they've only begun the process.

The reason I think it's naive to assume this will work as an injectible is that once the injections stop, whatever progress was made in terms of generating new follicles, will become susceptible to DHT.

So the exposure to Histogen has to be regular and long-term, in my opinion.

Which just increases the costs and increases the inconvenience.

And that's assuming it works good enough. The only credible evidence WE have of that are a few photos which show some results, but not great results. Just fair to middling. And the photos DON'T show patients whose scalps have been treated with this stuff. They just show what appear to be some new hair follicles and hair shafts growing in histological cross section slides. That and some mouse/rat studies, I think.

So, what do we have here? A complicated brew of chemicals that is being tested in SINGAPORE, and which has ZERO chance of becoming legal in North America anytime soon. Something uproven to grow cosmetically-acceptable amounts of hair on live patients, with just some obscure, anecdotal laboratory evidence to back it up, which, at best, doesn't even show good results, just slightly better than Propecia results. Something that may very well cause harmful side effects... but we don't really care about that, do we? Not as long as we get some meager peach fuzz to grow on our heads. Maybe with a skin tumor or two for good measure!

All that from a small US biotech company with a very checkered history of lawsuits, missteps, bad management, and false starts...

Don't hold your breath for this stuff.

roger_that is located in MARYLAND and he is available to meet: YES
email to arrange a meeting.

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