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Androgen signalling prevents hair cell differentiation (Hair Multiplication & Stem Cells Treatment)

posted by KO, 06.02.2012, 20:14


You are making up your own science here. How is it totally different when
you claim balding skin is different from normal hair growing skin? The
fact regardless of what is migrating in or out, transplanted hairs grow in
balding skin and cycles continuously (new dermal papilla re-generated).
Its not the skin, its the genetic predisposition of the hair follicle to
androgens.

When you transplant hairs, you're importing a substantial amount of skin. The dermal papilla of the transplanted hair is physiologically different. If it is all the same, why isn't it androgen sensitive?


There is a lot of evidence that the WNT pathway initiates cell
differentiation during the formation of hair follicles. There is also
evidence that androgens inhibit the WNT pathway which I posted. What
evidence can you furnish to show that the theory has been discarded?

------------

You need to read more carefully. We all know that the Wnt pathway is implicated in cell differentiation. However, the idea that simply injecting Wnt into skin will initiate HF neogenesis has been discarded. If it was that simple, we wouldn't be bald right now. If you want Wnt to grow hair you need to wound the skin. However, it has never actually been demonstrated that wnt applied to a wound can grow mature hair follicles.

I think Elaine Fuchs, who I believe is the author of that article has spoken out against this very notion.




KO is located in [NA] and he is available to meet: NO


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