Hair Loss - Androgen signalling prevents hair cell differentiation

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Androgen signalling prevents hair cell differentiation (Hair Loss Research & Clinical Trials)

posted by jarjarbinx, 06.02.2012, 23:59

» »
» » Where is there any evidence that the difference between transplanted
» hair
» » growing and not growing is the skin surrounding it? If that were the
» case,
» » wouldn't we now be culturing skin from the back of our heads and
» injecting
» » it into our balding scalps to around hair follicles.
»
»
» Why is it so difficult to understand that the dermal papilla is part of the
» skin? It is not a separate entity. Think about that. In balding skin
» during miniaturization DP cells migrate out of the hair follicle. Read
» Tobin or Jahoda's paper. Unless you think they're "making up their own
» science" as well.
»
»
»
» » Nobody has been (officially) injected with Wnt so how can you even make
» » such a claim.
»
» Not true. Please catch up, read Fathke's 2006 paper. If you want, rub
» lithium on your head, see if you grow hair.
»
»
» » and its inhibition in hair loss. The reason it isn't injected is
» because
» » some form of Wnt are implicated in the formation of tumours. There are
» » different varieties of the Wnt protein and not all are tumorigenic.
» » Nothing has been discarded and if anything researchers are focused on
» it.
»
» Overexpression of Wnt is implicated in tumors. They've done many
» experiments with mice engineered to overexpress Wnt. But point me to any
» experiment they've done that shows exogenous Wnt can grow mature hair
» follicles. No such experiment exists. It says so right in the Follica
» patent actually.
»
»
»
»
» And yes, the idea that injecting wnt into skin has been discarded. If it
» were that easy, I repeat, we would not be bald. We've known about Wnt's
» role in hair follicles for 10 years now. Cotsarelis would be a billionaire
» if that's all there was. Y

No it hasn't been discarded. Histogen has not discarded it and i don't think that follica has either. You are missing the point that Histogen for sure, and Follica possibly, are also adding other Wnts besides Wnts7a and they are also adding other growh factors. I am not saying that Wnt7a alone will do the job. Let me repeat that because it is not sinking into that thick skull of yours: I am not saying that Wnt7a along will do the job. I am saying that if you combine Wnt7a along with other Wnts and along with other growth factors that will do the job. And histogen has nearly proven that I am correct and you are wrong. You are saying that Wnts have no role in hair growth and the evidence says that you are wrong, wrong, wrong. The thing is that you also have to add other agents along with the Wnts. Do you get it yet?




jarjarbinx is located in [NA] and he is available to meet: NO

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