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Hair Loss Forum - micronedling for hair stimulation

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rachitadhurat

06.08.2013, 15:19
 

micronedling for hair stimulation (Drugs & Medications)

A RANDOMISED EVALUATOR BLINDED STUDY OF EFFECT OF MICRONEEDLING IN ANDROGENETIC ALOPECIA : A PILOT STUDY- published in Int J Trichology 2913
Author – Dr Rachita Dhurat, rachitadhurat@yahoo.co.in

Department of Dermatology, L.T.M.Medical College & General Hospital, Sion, Mumbai-400 022, Maharashtra, India


Abstract :
Introduction:
Dermal papilla is the site of expression of various hair growth related genes and a major target for androgen mediated events. Various research have demonstrated the underlying importance of Wnt proteins and wound growth factors in stimulating dermal papilla associated stem cells. Microneedling works by stimulation of stem cells and inducing activation of growth factors.
Materials and Method:
Hundred clinically diagnosed cases of androgenetic alopecia grade III/IV were recruited into 2 groups. One group was offered weekly microneedling treatment with twice daily 5% minoxidil lotion (microneedling group); other group was given only 5 % minoxidil lotion. After baseline global photographs, the scalp were shaved off to ensure equal length of hair shaft in all. Hair count was done in 1 cm2 targeted fixed area (marked with tattoo) at baseline and at end of therapy (week 12). The 3 primary efficacy parameters assessed were: change from baseline hair count at 12 weeks, patient assessment of hair growth at 12 weeks, and investigator assessment of hair growth at 12 weeks.
A blinded investigators evaluated global photographic response. The response was assessed by 7- point scale.
Results:
1. Hair counts
The mean change in hair count at week 12 was significantly greater for the Microneedling group compared to the Minoxidil group [ 91.4 versus 22.2 respectively].
2.Investigator evaluation
Forty patients in Microneedling group had +2 to +3 response on 7-point visual analogue scale, while none showed the same response in the Minoxidil group.
3. Patient evaluation
In the Microneedling group, 41[82%] patients reported more than 50% improvement versus only 2 [4.5%] patients in the Minoxidil group.
Unsatisfied patients to conventional therapy for androgenetic alopecia got good response with microneedling treatment.
Conclusion:
This study showed that dermaroller along with minoxidil treated group was statistically superior to minoxidil treated group in promoting hair growth in men with AGA for all 3 primary efficacy measures of hair growth.
Microneedling is a safe and a promising tool in hair stimulation and also is useful to treat hair loss refractory to minoxidil therapy .
.




rachitadhurat is located in [NA] and he is available to meet: NO


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Aran Linvail

08.08.2013, 07:06

@ rachitadhurat

micronedling for hair stimulation

Are you the same Rachita Dhurat who is the author of the study?




Aran Linvail is located in [NA] and he is available to meet: NO

---
Poster formerly known as "KO"


Post reply
Freddie555

09.08.2013, 04:23

@ Aran Linvail

micronedling for hair stimulation

micro-needling = derma-rolling?




Freddie555 is located in [NA] and he is available to meet: NO

---
"When true Hair Multiplication comes, it will arise out of the East." - John The Revelator, Feb. 18, 2001


Post reply
Aran Linvail

11.08.2013, 20:29

@ Freddie555

micronedling for hair stimulation

I think so. The photos posted in this study are impressive to say the least. Just search for the study title.




Aran Linvail is located in [NA] and he is available to meet: NO

---
Poster formerly known as "KO"


Post reply
rachitadhurat

23.12.2013, 19:59

@ Freddie555

micronedling for hair stimulation

microneedling in a technique which is being performed by a dermaroller instrument




rachitadhurat is located in [NA] and he is available to meet: NO


Post reply
rachitadhurat

23.12.2013, 20:01

@ rachitadhurat

micronedling for hair stimulation

The author, Dr Rachita Dhurat is located in Mumbai, India. www.rachitaskincentre.com




rachitadhurat is located in [NA] and he is available to meet: NO


Post reply
Aran Linvail

25.12.2013, 03:33

@ rachitadhurat

micronedling for hair stimulation

Do you represent the author?




Aran Linvail is located in [NA] and he is available to meet: NO

---
Poster formerly known as "KO"


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