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Study: licorice and peppermint decrease alpha five, sebum (Hair Loss Supplements)

posted by Pete2, 16.09.2007, 05:34
(edited by Pete2 on 16.09.2007, 05:50)

» Activity of herbal extracts on the control of sebum secretion.Accession
» number;04A0230063
» Title;Activity of herbal extracts on the control of sebum secretion.
» Author;UCHIUMI YOICHIRO(Maruzen Pharm. Co., Ltd., JPN) YAMAMOTO
» SUSUMU(Maruzen Pharm. Co., Ltd., JPN) MIZUTANI KENJI(Maruzen Pharm. Co.,
» Ltd., JPN)
» Journal Title;Fragr J
» Journal Code:G0987B
» ISSN:0288-9803
» VOL.32;NO.3;PAGE.53-57(2004)
» Figure&Table&Reference;TBL.4, REF.13
» Pub. Country;Japan
» Language;Japanese
» Abstract;Potential activity of herbal extracts on sebum secretion was
» studied. Among the herbal extracts tested, polyol-soluble licorice extract
» P-U (product name) derived from Glycyrrhiza inflata showed the most potent
» testosterone 5 .ALPHA.-reductase inhibition, androgen receptor binding
» inhibition and antimicrobial activities, which are closely related to
» sebum secretion. In addition to the findings on polyol-soluble licorice
» extract P-U, clove extract and peppermint extract showed testosterone 5
» .ALPHA.-reductase inhibition, arnica extract and rose fruit extract showed
» androgen receptor binding inhibition, alpinia speciosa root extract and
» scutellaria root extract showed estrogen receptor agonists, and sophora
» root extract showed antimicrobial activity. (author abst.)

I dont believe an androgen blockade topically will have any noticeable results with the substances that have been mentioned ie regrowth. Keep us updated.

» This is interesting because its HUMAN sebum secretions and HUMAN alpha
» five reductase being inhibited, as well as HUMAN androgen receptors being
» blocked.
» Ive been using peppermint oil mixed with PURIFIED water topically for a
» while now, and am happy with the results after an initial shed a month or
» so into it. I tested peppermint oil/purified water on one half of my chin
» for a few months, and it reduced beard hair pretty impressively compared
» with the other side. Peppermint oil is very cheap, and costs about four
» bucks an ounce. One ounce mixed with fifty or so ounces of purified water
» should last a good year.
» Some of the other herbals mentioned in this article like arnica root (a
» type of sunflower) and rose fruit (rose hips oil) can also be had very
» cheaply. Licorice might have a strong smell, but it was the most
» anti-androgenic of the lot.
» I became interested in mints as anti-androgens after reading about the
» spearmint tea hirsutism study from Turkey, and the men who complained of
» no libidio or low libidio after drinking peppermint tea, and the
» anti-androgenic effects of peppermint on lab rats. Ive noted that
» peppermint extract or peppermint oil is in the following shampoos: Paul
» Mitchel LemonSage Thickeing, Paul Mitchell Tea Tree, American Crew
» Thickeing (in the form of mint leaves), Jasons Tea Tree, Tricomin Shampoo,
» Tricomin Conditioner, its in one of HairCycle's products, and various
» "menthols" (which can be and often are synthetics) are in other shampoos
» also.

Menthol increases bloodflow and may help to stimulate the scalp.
However you dont want to over stimualte the scalp and make inflammation worse( unless you are using a Dual shampoo to lower inflammation and increase bloodflow). The key is to "drive down" inflammation first topically and then to improve the health/condition of the scalp before stimulating bloodflow (alone).

» I think it might be an effective ADDITION to taking our finasteride or
» dutasteride. I would not risk going off a proven treatment however, but
» think this would/should be quite helpful. I'd love to see further testing
» for alopecia, but realize that probably wont ever happen.
» If you google "peppermint and hair removal" or "licorice and hair removal"
» or "rose hips and hair removal" you will see that many compaines are
» obviously aware of the anti-androgenic properties of these substances.
» My current regimine...........finasteride, peppermint oil/purified water
» mix, prox-n, I use nizoral a couple of times a week also.
» Hope someone else can be helped by this for all my pals in the HM forum.


Pete2 is located in [NA] and he is available to meet: NO

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