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News on Follica (Hair Multiplication & Stem Cells Treatment)

posted by cal, 13.05.2016, 08:43
(edited by cal on 13.05.2016, 09:04)

Wounding has to be chronic because the perturbation of the skin just triggers temporary physiological changes which are associated with tissue healing -- release of growth factors, eosinophils, platelets, etc. These peak not too many days after the wounding incident and then gradually dissipate back down to baseline.

But for a hair follicle to remain viable and cycling, and to resist re-miniaturization from DHT, it must have these growth factors present continuously. Otherwise the same miniaturization process that happened before will take hold again.

The same principle applies with any drug therapy, by the way, like anti-androgens, minoxidil, etc. Triggering growth factor release via wounding is really no different, physiologically, from drug therapy. Both produce transient results and if withdrawn, the effect goes back to zero.

So you're saying the derms & guys who observe this phenomenon are ALL either mistaken or lying?

I have a handful of full-strength terminal hairs in the middle of the shiny bald skin of my temples. They were created most of a decade ago after dermabrading the area. I have done essenatially zilch to maintain them besides get some Nizoral on them during hair washing. I have even been plucking some of them to try and kill them again because they are slightly odd. (Are these hairs "lifetime permanent?" I dunno. But they are worth at least a decade & multiple hair cycles after a single wounding incident. And that's for accidental creation and zero maintenance efforts from then on. That already blows every other commercial MPB treatment out of the water.)

I am not alone in this at all. Look at the reports of scattered new terminals from guys who needle. Look at the occasional anecdotal stories of unusual regrowth after serious scalp wounds. Look at the Gefitnib cancer patients who grew thick dark patches of hair on areas that look like probable sunburn sites. Etc.

This phenomenon is real. It may never do us any practical good in the foreseeable future. But it's real. With how far off everything else is looking for commercial HM these days, we would be wretchedly stupid to brush this off as imaginary just because we don't understand it.

I have little faith in Cotsarelis's work restoring my hair in the next 20 years. I have absolutely no trust in his honesty. But he has been barking up the right tree for the most part. If the goal was commercially treating MPB rather than pure research then he definitely picked the smart thing to pursue a decade ago. It hasn't panned out yet, but neither has anything else. And most of the decent discoveries about hair during that time have Cots's fingerprints on them.

cal is located in [NA] and he is available to meet: NO

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