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treating hairloss from fat cells (Hair Multiplication & Stem Cells Treatment)

posted by cal, 29.09.2016, 01:31

AFAIK no amount of androgen suppression & blocking will do anything of the sort on humans. Not to a significant degree like this.

Even sex change/chemical castration won't do it. That combined with topical AAs (it's been done in the transgender community) should knock the androgen levels down far enough to see some of the effect. But in practice that doesn't give us nearly enough of the effect to explain the mouse results to my satisfaction. The reviving balded hairs don't seem to revive in the gradual "start backing up the process" sort of way seen with human hormone manipulation. No, it's such a full-throttle change that I think it's beyond the scope of any action anything we have seen in live humans. I'm saying it is not just a matter of degree IMO.

Seriously, can you imagine ANY amount of cutting off androgen stimulation in live humans that wakes up totally MPB'd follicles overnight like this? (A new drug, etc) If somebody published this result from blocking androgen stimulation alone we would never believe it. Not even close. We would be looking at their results and speculating about whether there was some other factor at work.

Besides - in order to produce much MPB-reversal activity (on live humans) with hormones, a female hormone profile's worth of Estrogens must be added to the mix as well. But if the mice are regrowing human hair because their androgens aren't affecting the human follicles, then you are stuck answering why the mice's Estrogens still do work on them.

IMO the more probable answer is that we don't understand MPB as well as we think we do. The fact that lab mice are a hopelessly ineffective model for studying MPB probably has something to do with it.

I don't know whether anyone has tried the mouse transplant thing with male facial or body hair grafts. That could be interesting because facial & body hair has basically the opposite reaction to androgens that scalp hair does.

cal is located in [NA] and he is available to meet: NO

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