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treating hairloss from fat cells (Hair Multiplication & Stem Cells Treatment)

posted by roger_that, MARYLAND, 30.09.2016, 12:04

The hair growth effect of JAK inhibitors doesn't have to be related to its immune-suppression activity. It can be related, or it could be a totally unrelated side effect of the drugs. Most powerful drugs like JAK inhibitors do a LOT of different things to the body, some related to their primary mode of action and some not.

An example of another class of drug that causes hair growth is Minoxidil, which was first sold as the anti-hypertensive drug Loniten. It has a wide variety of effects on body physiology. I mean VERY wide. Acutely, it dilates microscopic blood vessels. Chronically, it increases VEGF which causes more micro blood vessels to be made. It has effects on the kidneys, water retention, salt retention/excretion, etc. And those are just some of the effects. You can see that it was really hard for the researchers to figure out which, out of all the known effects of Minoxidil, was the one which causes hair growth. I believe they still don't know for sure.

The point is, we know that some immuno-suppressant drugs can cause hair growth, and we know that a few things happen in MPB that seem related to the immune system (like increases in some kinds of T-lymphocytes in some people, I think)... On the other hand, lots of stuff that normally happens in auto-immune diseases DOES NOT happen in MPB. In fact, the major hallmarks of auto-immune disease like a known Antigen-Antibody relationship, do not even show up in MPB.

What has never been proven is that MPB is an auto-immune disorder, or that the JAK inhibitors' immune-suppression effects are what's causing the hair growth.

roger_that is located in MARYLAND and he is available to meet: YES
email to arrange a meeting.

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