Topical dutasteride (Topicals & Shampoos)
» » So what about the NEW enzyme that starts to form after a day or so?
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» Byran, good question. How long would it take for the enzyme to reappear?
To get a reasonable idea of that, take a look at this often-posted graph from a medical journal study:
http://www.geocities.com/bryan50001/graph8.htm
It shows actual measured serum DHT levels for up to 7 days in human volunteers who took various SINGLE doses of finasteride. Even though finasteride is pretty much out of the body (or out of the blood, at least) a day or two after the last dose that you take, nevertheless it took up to a week or two for the blood levels of DHT of these test-subjects to get back to normal after those test doses. That's because the regeneration rate of the type 2 enzyme ITSELF is rather slow. Once finasteride or dutasteride knocks it out, it takes a while for new, "fresh" enzyme to be synthesized within the cell (finasteride and dutasteride are both considered to be irreversible inhibitors of the type 2 enzyme).
» The duta should stay in the follicle area for a while, i doubt it would
» all be systemically absorbed into the body that quickly, but just a guess.
Then I guess that would be the main point of contention here! I don't know of any evidence at all to suggest that dutasteride (or finasteride, for that matter) would hang around for such an incredible amount of time within the confines of a hair follicle, or just in the skin. I think it would last for a matter of MINUTES, not MONTHS!
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Bryan is located in [NA] and he is available to meet: NO
Complete thread:
- Topical dutasteride
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