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Topical dutasteride (Topicals & Shampoos)

posted by rooster, 17.12.2007, 20:43

» » So Basically you are saying that once you take finasteride and Duta
» » you'll never have that type 2 enzyme again in your metabolism ?!
» Your question is a little ambiguous, but what I'm saying is that once a
» molecule of the 5a-reductase type 2 enzyme binds to either finasteride or
» dutasteride, it's essentially destroyed as a DHT-producing entity. That
» individual molecule will no longer be able ever to produce DHT again.
» Only new, freshly synthesized type 2 molecules that haven't yet been bound
» by fin or dut will be able to do that.
» .

Which leaves us to the real question, how fast does DHT resynthesize? If the enzyme in the skin has bound to duta or fina i really feel the affects could last a week or more, i don't beleive the drug would disperse in minutes. JUST MY OPINION.

So the two questions for me:

How fast would DHT resynthisize in the skin, aka scalp. Secondly, does the enzyme bound by duta keep the active duta in the area of the scalp for up to a week or does it get systemically absorbed?

rooster is located in [NA] and he is available to meet: NO

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