Deprecated: The each() function is deprecated. This message will be suppressed on further calls in /home/hairsite/public_html/hair-loss/functions.php on line 155
Hair Loss Forum -

March 2017 - Trending Topics in our new forum

 Stem cell hair restoration results - Dr. Cole vs Histogen vs RepliCel.
 Dr. Paul Kemp, CEO of HairClone answers questions about follicle banking.
 RepliCel year 2017 forecast for RCH-01 cell based hair regeneration.
 Dr. Cole to start stem cell hair restoration trial in the US.
 Dr. Umar's 6500 grafts life saving repair procedure for transplant victim.
 FUE donor harvesting, what you must know when choosing a clinic.
 Dr. Koray Erdogan raises the standard in FUE artistry skills.
 Dr. Arvind on how to formulate your own toxic free shampoo.
 Conference & FREE hair restoration consultations; cities worldwide.

This is a READ ONLY forum.
Access our brand new platform at HairSite New Forum to continue the discussion on these topics that you are interested in. All contents and discussions have been transferred to our new forum at
  HairSite New Forum

Log in | User | Register

Topical dutasteride (Topicals & Shampoos)

posted by rooster, 18.12.2007, 16:27

» No. I believe we are confusing the LEVEL and the PRODUCTION RATE. If you
» pay attention to these graphs posted by Bryan, they show that the serum
» level is divided by 1.5, 2 or 3. This is a lot. Whereas the finasteride
» has become inactive after a few hours, maybe because of its quite short
» half life and above all because it has been chemically consumed to
» neutralize DHT molecules, the endocrine production of DHT (which I
» believe is at least as active as before the finasteride intake), is simply
» insufficient to get this level to its previous value within, say, a day or
» two. If your assumption was right, we should see a landing on the curve,
» which we do not see. What's more if you look closely at the curves, you
» can see how the average slope is way steeper for higher finasteride
» concentrations, which explains why all curves get near one to the other
» after 7 days. It means that the more DHT you inhibit, the more fresh
» dht is rapidly produced. If not, explain to me how the 5mg finasteride
» could be in the vicinity of the 0.2 or 0.04 mg after 7 days whereas the
» DHT was way more severely suppressed in the first place.

Scalp DHT suppression, which is felt to be correlated to a drug’s effectiveness, was measured and showed that finasteride decreased scalp DHT by 32%, dutasteride 0.5 mg by 51% and dutasteride 2.5 mg showed 79% suppression. DHT concentration in the blood was decreased 73% by finasteride, 92% by dutasteride 0.5mg. and 96% by dutasteride 2.5 mg . The speed by which drugs are eliminated from the body are measured by a value which is called “half-life”. The half-life of finasteride is six to eight hours whereas for dutasteride it is four to five weeks, which means that when one stops taking dutasteride, it will take several months before the drug is out of the system. When blood DHT was measured in these patients 12 weeks after stopping the medication, the finasteride treated patients had a normal DHT level while the dutasteride 0.5 still showed a 10% decrease and the dutasteride 2.5 mg treated patients still had significantly lowered DHT levels.

rooster is located in [NA] and he is available to meet: NO

Complete thread:

120100 Postings in 12546 Threads, 6122 registered users
Hair Loss Forum | Admin contact

This is a READ ONLY forum.
Access our brand new platform at HairSite New Forum to continue the discussion on these topics. All contents and discussions have been transferred to
HairSite New Forum

Disclosure: This is an advertising site for our paid sponsors & advertisers. The contents, videos & photos on HairSite are provided by paid sponsors and are not endorsed by HairSite in any way. The recommendations, results, and representations made by our sponsors/advertisers do not reflect the opinions of HairSite. This site is to showcase successful hair restoration results only. It is not the mandate of this site to engage in the discussion of failed, unsuccessful procedures, lawsuits, litigations or complaint cases; comments of such nature, including external links, may be removed from the forum. Notify any false, defamatory, misleading or inappropriate user generated contents for immediate removal from the forum. Also read Terms of Use & Privacy Statement |  HairSite advertisers: ASMED | Dr. Bhatti | Dr. Bisanga | Dr. Cole | Dr. Hakan Doganay | Dr.Epstein | Dr. Jones | Dr. Halder | Hasson & Wong | Dr. Klein | Dr. Madhu | Dr. Mwamba | Dr. Donald Ng| Dr. Poswal | Dr. Rahal | Dr. Razack | Dr. Reddy | Dr. Umar | Dr. Woods | DHI Global | HDC Clinic | |Lasercomb | Reviva Clinic | Ziering Medical|