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Topical dutasteride (Topicals & Shampoos)

posted by Bryan, 19.12.2007, 07:19

» Frankly, I don't know what we can make of this information.
» 1) a quick turnover in vitro generally points to a quick turnover in vivo.
» But a slow turnover in vitro doesn't necessarily induce a slow one in vivo

BRM, you have a talent for posting statements which I just can't understand at all! :-)

» 2) Above all, the indication they give is about the HALFLIFE of these
» complexes. But what do we care? These complexes are the dihydrofinasteride
» complexes AFTER the chemical reaction, that is, inert products unable to
» neutralize any other DHT molecule. The only relevant point is the
» halflife of the reactant: finasteride and dutasteride themselves. And once
» again, because of this, your point is a good one.

Who SAYS we care about the half-life of the enzyme/drug complexes?? Obviously, all we do care about is the half-life of the finasteride and dutasteride. I don't understand the point of your paragraph above.

.




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