Deprecated: The each() function is deprecated. This message will be suppressed on further calls in /home/hairsite/public_html/hair-loss/functions.php on line 155
Hair Loss Forum -

March 2017 - Trending Topics in our new forum

 Stem cell hair restoration results - Dr. Cole vs Histogen vs RepliCel.
 Dr. Paul Kemp, CEO of HairClone answers questions about follicle banking.
 RepliCel year 2017 forecast for RCH-01 cell based hair regeneration.
 Dr. Cole to start stem cell hair restoration trial in the US.
 Dr. Umar's 6500 grafts life saving repair procedure for transplant victim.
 FUE donor harvesting, what you must know when choosing a clinic.
 Dr. Koray Erdogan raises the standard in FUE artistry skills.
 Dr. Arvind on how to formulate your own toxic free shampoo.
 Conference & FREE hair restoration consultations; cities worldwide.

This is a READ ONLY forum.
Access our brand new platform at HairSite New Forum to continue the discussion on these topics that you are interested in. All contents and discussions have been transferred to our new forum at
  HairSite New Forum

Log in | User | Register

Study: Estrogen plays a role in hair loss (Topicals & Shampoos)

posted by ipod, 05.01.2008, 20:39

This study is not really clear on how estrogen moderates hair loss but it sure does confirm that estrogen has a role to play in hair loss.

J Invest Dermatol. 2004 Jan;122(1):7-13.

Topical estrogen accelerates hair regrowth in mice after chemotherapy-induced alopecia by favoring the dystrophic catagen response pathway to damage.

Ohnemus U, uNalan M, Handjiski B, Paus R.

Department of Dermatology, University Hospital Hamburg-Eppendorf, University of Hamburg, Hamburg, GermanyDepartment of Dermatology, Charite, Humboldt-University, Berlin, Germany.

Estrogen receptor ligands are important modulators of skin physiology and are involved in the control of normal hair follicle cycling. Here, we have studied the effects of topically applied 17-beta-estradiol on pathologic hair follicle cycling as seen during chemotherapy-induced alopecia, one of the major unresolved problems of clinical oncology. For this study we employed a well-established murine model that mimics chemotherapy-induced alopecia in humans. For precisely quantifying the area of hair loss and hair regrowth in this model in vivo, we developed a simple planimetric assay (dotmatrix planimetry). We show that topical 17-beta-estradiol significantly alters the cycling response of murine follicles to cyclophosphamide, whereas the estrogen antagonist ICI 182.780 exerted no such effects. Initially, topical 17-beta-estradiol enhanced chemotherapy-induced alopecia significantly by forcing the follicles into the dystrophic catagen response pathway to hair follicle damage, whereas follicles treated by ICI 182.780 or vehicle shifted into the dystrophic anagen response pathway. Consequently, the regrowth of normally pigmented hair shafts after chemotherapy-induced alopecia was significantly accelerated in the 17-beta-estradiol treated group. Our data encourage one to explore topical estrogens as a potential stimulant for hair re-growth after chemotherapy-induced alopecia.

PMID: 14962083

ipod is located in [NA] and he is available to meet: NO

NW3 -
Propecia /Saw Palmetto
Topical Spiro / Rogaine Foam (quit REMOX IV)
High does vitamin C / Lysine / Nizoral / Tea Tree Oil Shampoo

Complete thread:

120100 Postings in 12546 Threads, 6045 registered users
Hair Loss Forum | Admin contact

This is a READ ONLY forum.
Access our brand new platform at HairSite New Forum to continue the discussion on these topics. All contents and discussions have been transferred to
HairSite New Forum

Disclosure: This is an advertising site for our paid sponsors & advertisers. The contents, videos & photos on HairSite are provided by paid sponsors and are not endorsed by HairSite in any way. The recommendations, results, and representations made by our sponsors/advertisers do not reflect the opinions of HairSite. This site is to showcase successful hair restoration results only. It is not the mandate of this site to engage in the discussion of failed, unsuccessful procedures, lawsuits, litigations or complaint cases; comments of such nature, including external links, may be removed from the forum. Notify any false, defamatory, misleading or inappropriate user generated contents for immediate removal from the forum. Also read Terms of Use & Privacy Statement |  HairSite advertisers: ASMED | Dr. Bhatti | Dr. Bisanga | Dr. Cole | Dr. Hakan Doganay | Dr.Epstein | Dr. Jones | Dr. Halder | Hasson & Wong | Dr. Klein | Dr. Madhu | Dr. Mwamba | Dr. Donald Ng| Dr. Poswal | Dr. Rahal | Dr. Razack | Dr. Reddy | Dr. Umar | Dr. Woods | DHI Global | HDC Clinic | |Lasercomb | Reviva Clinic | Ziering Medical|