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Avodart and DHT levels. (Drugs & Medications)

posted by boris342002, 03.04.2008, 23:28

» » This question has been asked many many times. From the second set of
» graphs
» » above, it seems obvious that dutasteride could be taken only once every
» 1,
» » 2 or even 3 weeks without seeing any relevant change in the DHT serum
» » level.
»
» Sure, but only if you take an INCREASED DOSE (more than just a single
» Avodart capsule) once every 1, 2, or 3 weeks. To get the same amount of
» DHT suppression as taking an Avodart every day, you'd have to take 7
» Avodart capsules once a week, or 14 Avodart capsules once every two weeks,
» or 21 Avodart capsules once every 3 weeks. See how it works? :-) You
» still have to get the same average dose of dutasteride, to achieve
» the same average level of DHT suppression.
»
» » I remain a bit skeptical though about the long term efficiency. After
» » all this drug has been designed against BPH and I imagine that Glaxo
» was
» » aware of the apparent inertia of the DHT serum level after a single
» intake
» » of dut.
»
» I'm not sure what you mean by that. There's not much "inertia" after
» taking just a SINGLE Avodart capsule, because it obviously hasn't been
» building-up in the bloodstream for several weeks or months. But the
» "inertia" that you think you see after you've been taking it for a long
» time comes from the ACCUMULATED amount of the drug in your bloodstream,
» not any one single capsule that you happen to take on a given day.
»
» » Why on earth did they adjust posology at one a day if one every
» » 3 days was enough.
»
» Because one Avodart capsule every 3 days is NOT enough! :-) Not enough to
» achieve the intended level of serum DHT reduction, anyway (about ~90% or
» so).
»
» Dutasteride is a DOSE-DEPENDENT drug. You get increasingly more DHT
» suppression as the dose increases, thanks to the fact that it hangs around
» in the bloodstream so long.
»
» .


Hi Bryan,
So what would you say if at max. I took a capsule (0.5mg) on Monday, Wed, Fri, Sun, in other words, rest one day in btw. do you think Im wasting my time and money. What about resting 2 days.
How can you be so sure of your statement and what do you say about the graphs posted above then?
Cheers




boris342002 is located in [NA] and he is available to meet: NO


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