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Hair Loss Forum - Stem Cell HM Result, 4 month@Dr. Nigam

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drnigam

18.05.2013, 16:47
(edited by drnigam, 18.05.2013, 17:04)
 

Stem Cell HM Result, 4 month@Dr. Nigam (Hair Multiplication & Stem Cells Treatment)

Dear Friends,



I am happy to share this pure HM result of 4 months with you. I came to know about this patient day before yesterday. He lives 2 and half hour from my Andheri clinic. To share this post I sent a cab to pick up & drop him for our forum members. Thankfully he agreed for the same.



We extracted few grafts from his donor scalp on 7th Jan 2013 and took 3 before pictures on 5th Jan 2013. His procedure has not been undertaken at my main clinic but at one of my mini clinic which is located outskirts of Mumbai.



On 7th Jay 2013 he received the 1st shot of progenitor activated stem cell injection and 2nd shot of multiplied stem cell was given in the 1st week of April 2013.



I took his picture and video today at my clinic and few pictures were also taken at my mini clinic on 13th May 2013.



These picture are not for Dr. Nigam's promotion alone but it is also dedicated to all the researcher who have been working on mice. Other companies which are doing their clinical trials....... as these pictures is a great news for both HT doctors and hair loss community that in very near future we will be able to give consistent results to most of our patients........ As on today not all patients will be as lucky as this guy. I am expecting double or triple of this density by next 1 year because I am yet to give him DP CELL INJECTION, TRICHOGENIC 3D SPHEROIDAL DP CULTURE, 2 MORE INJECTIONS OF MULTIPLIED INJECTION, ONCE A MONTH GROWTH FACTOR and this patient is not on any Finasteride or minoxidil. I humbly would like to answer certain critics who used to laugh at me whenever I say 30 K to 40 K hair follicles generation after HM injection on certain patients, now the proof is in front of you.



This is interesting case to followup for next 1 year with more HM procedure to be done on him with new protocols. I do not have his before videoscopic picture but I have taken his videoscopic pictures today. Upto now I have not injected on his temples but as in the coming months I will work on his slick bald temples, let us see what will be the result.



Similarly I would like to see that am I able to lower his hair line with HM injection alone?



In the morning I have seen one more patient with good result, I will post his pictures after 2 months when his scalp becomes more denser. By the way one French forum moderator who is also a forum member before me on HT and BT is coming on 25th May for HM, DP Cells & Doubling. Another forum member is coming tentatively on 15th July.

Such case give us hopes that if certain scalp can get such results then in future it will increase. No despair any more, skeptics please be aware, cure is not far away and it will happen on this forum itself.

One bad news abstract submission of presentation at international society for hair restoration (ISHRS 2013) is closed on 30th March 2013 and unfortunately I missed the deadline and hence there are very less chance that I will be presenting my case of scarless HT, HM, DP. Although I will be mailing the same to the scientific community, let’s see if I will be able to post the presentation on time. Otherwise maximum what I can do is to be a part of Q&A discussion at San Francisco.

Before
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http://www.drnigams.net/images/Savio/Before/Large/1.jpg

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http://www.drnigams.net/images/Savio/Before/Large/2.jpg

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http://www.drnigams.net/images/Savio/Before/Large/3.jpg

After 4 months

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http://www.drnigams.net/images/Savio/After/Large/5.jpg

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http://www.drnigams.net/images/Savio/After/Large/6.jpg

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http://www.drnigams.net/images/Savio/After/Large/7.jpg

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http://www.drnigams.net/images/Savio/After/Large/8.jpg

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http://www.drnigams.net/images/Savio/After/Large/9.jpg

[image]
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http://www.drnigams.net/images/Savio/After/Large/10.jpg


Before-After
[image]
Click the below link for enlarge image
http://www.drnigams.net/images/Savio/B-A/Large/1.jpg

[image]
Click the below link for enlarge image
http://www.drnigams.net/images/Savio/B-A/Large/2.jpg

Video Link
http://youtu.be/H19whebfAKY



drnigam has 1 Personal Journal(s). Click here to view
drnigam is located in [NA] and he is available to meet: YES
email hairsite@aol.com to arrange a meeting.

Tom Vercetti

France,
18.05.2013, 17:10

@ drnigam

Stem Cell HM Result, 4 month@Dr. Nigam

it's impressive ! Are you still injecting PRP ?




Tom Vercetti is located in FRANCE and he is available to meet: NO

tricho

18.05.2013, 17:20

@ drnigam

Stem Cell HM Result, 4 month@Dr. Nigam

Any idea when we can expect an update on OBI's HM case ?




tricho is located in [NA] and he is available to meet: NO

KO

18.05.2013, 19:12

@ drnigam

Stem Cell HM Result, 4 month@Dr. Nigam

Congratulations Dr Nigam! This is incredible. I don't think any posters will have a problem with this patients crown whorl. :)

To clarify a point, this patient received fresh epithelial stem cells converted to progenitor cells, and then multiplied stem cells converted to progenitor cells? (can you multiply and convert stem cells?) On top of that, he received no other treatments?



Originally Posted by drnigam

We extracted few grafts from his donor scalp on 7th Jan 2013 and took 3 before pictures on 5th Jan 2013. His procedure has not been undertaken at my main clinic but at one of my mini clinic which is located outskirts of Mumbai.


On 7th Jay 2013 he received the 1st shot of progenitor activated stem cell injection and 2nd shot of multiplied stem cell was given in the 1st week of April 2013.





KO is located in [NA] and he is available to meet: NO

GoneWithTheHair

Australia,
18.05.2013, 23:56

@ KO

Stem Cell HM Result, 4 month@Dr. Nigam

Wow exciting stuff.... When the process is tweaked to maximum performance I'm going to fly bald and fly Mumbai ....




GoneWithTheHair is located in AUSTRALIA and he is available to meet: NO

jarjarbinx

19.05.2013, 00:57

@ GoneWithTheHair

Stem Cell HM Result, 4 month@Dr. Nigam

1. Did Dr. Nigam take these pics or did someone else take these pics?

2. How can Dr. Nigam tweak the treatment to make it better?



Originally Posted by GoneWithTheHair

Wow exciting stuff.... When the process is tweaked to maximum performance I'm going to fly bald and fly Mumbai ....





jarjarbinx is located in [NA] and he is available to meet: NO

drnigam

19.05.2013, 01:54

@ KO

Stem Cell HM Result, 4 month@Dr. Nigam

KO,
As you know in another thread by roger..their was confusion in members understanding regarding what is a progenitor cell and how is different from stemcells in the hair follilce...
1)Progeny dictionary meaning..derived from another..or for example progeny means a persons own child...so progenitor cells in a follicle are child or offspring of follicle stemcells...
2)This means progenitor cells are progeny or derived from another cells..in the case of the follilce..progenitor cells are derived from follilce stemcells..in simple language.
In isolation and culture of follilce stemcells.... follilce stemcells which physiologically are used for wound healing or follilce repair or regeneration..

when isolated in vitro in lab..are firstly separated from surrounding cells...than after enzymatic process are activated and are now called progenitor cells...and they will now follow a limited lineage or a particular type of cells at the end when they will differentiate..

There are still few more different definition of progenitor cells..like they can multiply for limited cycles and will than differentiate to their destined lineage cells..
when body wants follicle stemcells or dp cells to help in wound healing..they will start multiplying..and now called progenitor stemcells or precursor cells etc.by different names like transient amplifying cells and have upward descend towards epidermis for healing...similarly they become another type of progenitor cells when they are asked to go down towards dp to repair or regenerate follilce..
THIS IS CALLED SWITCHING modes of follicle stemcells invivo...

Yes, progenitor cells can be cultured as stemcells can be cultured because it is it's progeny...i hope there is no more confusion because of misunderstanding of, cotsarelis mentioning progenitor cells in different context of pgd2 study...
When cotsarelis says...we need active or progenitor cells..it means as study confirms..even in anagen,
stemcells of follicle are in dormant inactive state ...but with right signalling converts to active progenitor cells when needed in vivo..

except in case of AGA scalp areas where this function is inactive of conversion to active progenitor state...due to multiple reasons...

On day 0 injection of stemcells..i don't have needed time to multiply stemcells after its activation...hence i only isolate and activate these stemcells which can also be called progenitor cells...and in 6 weeks these progenitor cells will multiply to higher number and are ready for injection with therapeutic dosage...some people may still use the word progenitor in different context..but for our understanding in case of follicle..this is commonly the explanation..

after all what's in a name..it is in it's functioning....


Congratulations Dr Nigam! This is incredible. I don't think any posters will have a problem with this patients crown whorl. :)

To clarify a point, this patient received fresh epithelial stem cells converted to progenitor cells, and then multiplied stem cells converted to progenitor cells? (can you multiply and convert stem cells?) On top of that, he received no other treatments?



Originally Posted by drnigam

We extracted few grafts from his donor scalp on 7th Jan 2013 and took 3 before pictures on 5th Jan 2013. His procedure has not been undertaken at my main clinic but at one of my mini clinic which is located outskirts of Mumbai.


On 7th Jay 2013 he received the 1st shot of progenitor activated stem cell injection and 2nd shot of multiplied stem cell was given in the 1st week of April 2013.


Originally Posted by KO




drnigam has 1 Personal Journal(s). Click here to view
drnigam is located in [NA] and he is available to meet: YES
email hairsite@aol.com to arrange a meeting.

RickH

19.05.2013, 04:41

@ drnigam

Stem Cell HM Result, 4 month@Dr. Nigam

That is a very impressive result, Dr Nigam!

You wrote, "As [of] today not all patients will be as lucky as this guy." Why? Why is his result better than the result others can expect?




RickH is located in [NA] and he is available to meet: NO

jarjarbinx

19.05.2013, 04:44

@ RickH

Stem Cell HM Result, 4 month@Dr. Nigam

Dr. Nigam has more work to day to get the treatment perfected. I'm going to start the process of getting a passport but I'm not buying a plane ticket to India until it's clear that Dr. Nigam has worked all of the bugs out. He's going in the right direction but he needs to keep pushing the envelope, perfect the treatment, and make it work for everyone. Then it will be time to buy an airline ticket, but right now it is time to get our passports in order.


Originally Posted by RickH

That is a very impressive result, Dr Nigam!

You wrote, "As [of] today not all patients will be as lucky as this guy." Why? Why is his result better than the result others can expect?





jarjarbinx is located in [NA] and he is available to meet: NO

KO

19.05.2013, 06:35

@ jarjarbinx

Stem Cell HM Result, 4 month@Dr. Nigam

You apparently have not noticed, but Dr Nigam is considering doing an informal (or formal?) clinical trial for topical application of growth factors like KGF, VEGF, Follistatin etc....you know the stuff you keep talking about.




KO is located in [NA] and he is available to meet: NO

jarjarbinx

19.05.2013, 07:35

@ KO

Stem Cell HM Result, 4 month@Dr. Nigam

I'm aware. Cool eh? Why did you think I didn't know this?

I am a little concerned that he probably won't use ALL of the correct growth factors but at least he is using some of the correct growth factors.

AND I think that there may be a way to get around the fact that he's unable to use all of the correct growth factors. CHECK THIS OUT KO: Those growth factors that he can't use may be more not be necessary if he also uses stem cells and progenitor cells. Of course he should use all of the correct growth factors that he can use but there are some growth factors that he can't use but maybe he can get around that problem by adding progenitor/stem cells which he is already working with.

He can also read Histogen's published material if he wants to know which growth factors he should NOT use because Histogen has identified the growth factors which should be avoided due to cancer potential. I can get him that info if he wants me to. If my memory serves me well I think the growth factors he should avoid are Wnt5 and Wnt3.

What do you think KO? Do you think we're getting close? I think that we might be getting very close. I think you and I should start organizing the paperwork so we can get passports. I don't think we should fly to India yet but we should start getting our passports in order so we are prepared.

Growth Factors + Stem cells + progenitor cells + anything else that might help + repeat injection dates.

I'm getting giddy KO.

What do you think KO? Does this sound promising?


Originally Posted by KO

You apparently have not noticed, but Dr Nigam is considering doing an informal (or formal?) clinical trial for topical application of growth factors like KGF, VEGF, Follistatin etc....you know the stuff you keep talking about.





jarjarbinx is located in [NA] and he is available to meet: NO

Desmond84

19.05.2013, 13:26

@ jarjarbinx

Stem Cell HM Result, 4 month@Dr. Nigam

Dear Dr. Nigam,

I opened an account on Hairsite just to post this on this thread:

First of all, CONGRADULATIONS to both you and all the hairloss sufferers following this thread as you are undoubtedly on the right path :)

These results are out of this world! I'm sure Aderans is watching you and these forums closely!

Thank you so much for being so ACTIVE in bringing such new solutions to the hairloss community. I personally love your charismatic personality and open-minded attitiude...

Keep up this great work and thank you for keeping us in the loop.

-Desmond




Desmond84 is located in [NA] and he is available to meet: NO

KO

19.05.2013, 17:10

@ jarjarbinx

Stem Cell HM Result, 4 month@Dr. Nigam

Unless Histogen is flat out lying about their work, we should be able to replicate it to some extent, especially Dr Nigam, with his lab. He can culture neonatal foreskin fibroblasts to produce these growth factors. So yeah, IF histogen is not lying, we are close.

I am Indian myself, so going there is not a huge problem, my question is really, what stage is Dr Nigam in the development process and which protocol (growth factors/HM/DP culture) is most mature?




KO is located in [NA] and he is available to meet: NO

drnigam

19.05.2013, 17:25

@ RickH

Stem Cell HM Result, 4 month@Dr. Nigam

RickH,
For a claim of success of HM the patient should get approx.60 to 100 new follicles(not grafts) minimum per sqcms of injected scalp area.Although this patient is and will be having much higher density...in coming months.
These are othe such results atleast prove that what autologous multiplied stemcells can do independently.
But there is also this puzzle why not similar results are seen in all scalps injected ,what is stopping the activation or new follicle growth in those AGA scalp.
1)One possibilty is that they are missing dp/ds trichogenic cells and higher dosage cultured dp cells..which problem is now rectified by injectin dp/ds fresh isolated cells and it's injection given to the patients in our new protocol.
2)The other possibilty was may be missing growth factors,which is now also a part of our new protocol.VEGF,FGF,FOLLISTATIN,MAY BE WE INTRODUCE WNT10B WHICH IS SAFER THAN OTHER WNT'S and repeat these injections once amonth(for outpatients we will provide them the growth factor ampoules or gel form to take with them and get it injected from their local medical provider or nurse..as per my prescription suggested)
With my protocol of may/june 2013...results should be more consistent and better...that.s what i hope..will come to know the results in coming months...
3)Result should further improve with aggregated dp culturre cells..which requires culturing little longer than 6 weeks.Luckily gerd has already done this ,i am aware of the technique to be used..
4)Another possibile missing link could be 3d spgeroidal culture with scaffolds and supllimentation of ingredients to improve trichogenecity of cultured dp/ds cells and it's injection...i have ordered most of the stuff of 3d spheroidal culturelike matrigel,hanging drop system,but need to order few more stuff..and will start culturing the same from 1/2week of june...and would inject the same cultured cells by august to 1st patient and observe the results in coming months...may be than i may change my statement...THAT ALL BUT FEW SCALPS CAN EXPECT SIMILAR RESULTS...
5)Than may be we will have to culture the epithelial stemcells and 3d spheroidal dp culture together rather than separately.. in a special layered culturing ...
And ofcourse patients should continue their medical topical prescription for MPB.
This patient result is with my old protocol,with 2 injections of autologous stemcells..only active progenitor cells on day o in jan and multiplied stemcell injection in 1st week of april...now i will give him dp/ds cell inj,
dp culture injection,growth factor inj once a month...and i am very optimistic he will have double this density by this year end...
He is not on any medication(like fina or minoxidil0 for hair loss as on today..


Originally Posted by RickH

That is a very impressive result, Dr Nigam!

You wrote, "As [of] today not all patients will be as lucky as this guy." Why? Why is his result better than the result others can expect?




drnigam has 1 Personal Journal(s). Click here to view
drnigam is located in [NA] and he is available to meet: YES
email hairsite@aol.com to arrange a meeting.

drnigam

19.05.2013, 17:47

@ Desmond84

Stem Cell HM Result, 4 month@Dr. Nigam

If i am correct ,you are the same desmond84 of the other forum,
And are u a pharmacist..it would in discussions for topical fina..if it's true.
Welcome you to HS..looking forward to application based solutions and opinions from your side...
Yes,KEN,WASHNIEK had asked me to mail..and i invited him to india to have a look what we are doing..i am yet to mail him..may be shortly..
and will also meet stenn and washniek at San Fransisco..to exchange if they are doing anything new to improve on HM..
i think with the help of great researchers like..FUCHS.JAHODA.HIGGINS.CHRISTIANO,PHILLIPOT,KURT STENN,TYOSHIMA the lead researcher of TSUJILAB (who was also their at wchr congress)
,GERD,RAJESH THANGAPA from pennsylvania and others ..all we have to do is see if their research on mice or human bioengineered skin grafted on mice with experiments of injecting human stem.dp cells.. and their experiments on factors affecting growth of human hair follilce in vitro in lab ..
FACTS not information can becan be replicated at the human scalp with injections and minitrial at the lab..and only on ingredients ,which are safe to use..

Originally Posted by Desmond84

Dear Dr. Nigam,

I opened an account on Hairsite just to post this on this thread:

First of all, CONGRADULATIONS to both you and all the hairloss sufferers following this thread as you are undoubtedly on the right path :)

These results are out of this world! I'm sure Aderans is watching you and these forums closely!

Thank you so much for being so ACTIVE in bringing such new solutions to the hairloss community. I personally love your charismatic personality and open-minded attitiude...

Keep up this great work and thank you for keeping us in the loop.

-Desmond




drnigam has 1 Personal Journal(s). Click here to view
drnigam is located in [NA] and he is available to meet: YES
email hairsite@aol.com to arrange a meeting.

Noyznarcos

19.05.2013, 18:24

@ drnigam

Stem Cell HM Result, 4 month@Dr. Nigam

---




Noyznarcos is located in [NA] and he is available to meet: NO

Noyznarcos

19.05.2013, 18:27

@ drnigam

Stem Cell HM Result, 4 month@Dr. Nigam

Doctor Nigam that most lay users of this forum wants to see are pictures and certified independent safety. Stop.

The issues tecnicne dp cell, 3d culture spgeroidal for someone who is not a graduate student in biomedical engineering is how to speak Arabic.

Doctor avoids, please, talk about 100 different things you want to do in the future.

Many of us in these forums want something NOW to be able to enjoy life to 100%, and not to think about this problem.

Since you say that there are no problems with the doubling, and you can engage 20,000 uf in 1 year. Well Fixed an affordable price 10-12 K and begins to work.

How's that for a solution, the rest is just talk and campaign promises that we do not need.

I hope you understand my speech.

thanks




Noyznarcos is located in [NA] and he is available to meet: NO

StinkySmurf

19.05.2013, 18:59

@ drnigam

Stem Cell HM Result, 4 month@Dr. Nigam

Hi Dr. Nigam,

How long do you think these results will last or is this a permanent improvement?

Thanks!




StinkySmurf is located in [NA] and he is available to meet: NO

jarjarbinx

19.05.2013, 20:39

@ KO

Stem Cell HM Result, 4 month@Dr. Nigam

KO if and when it comes time for me to go to India I would like your advice on making the trip. Are you in America? I wonder if we could plan this so that a bunch of take this trip together (if and when Dr. Nigam gets the right mixture of growth factors, cells, and other materials to get great results nearly every time) and perhaps save some money on airline tickets lodging and anything else.

I'm going to request my original birth certificate on Wednesday because I can call the hospital I was born at Wednesday since that is my day off. I need to secure my birth certificate and then get some passport photos and apply for a passport. I figure all of this will take 2 - 4 months. I figure we should know better where things are at with Dr. Nigam's growth factors + cells + whatever to grow lost hair. But if we work together we might get better deals on things like airfare and hotels.

Also, I don't think we should say anything outside of the Hairsite forums because we don't want a million people flying to India to get treatment from Dr. Nigam since that will create a waiting list to see him. We want to get all the Hairsite posters done first and then perhaps go on TV or something to let everyone see our results and recommend Dr. Nigam to the rest of the world after we are done getting our treatments and our hair has grown out so that we can show the world the great success if we can get this cured soon.

And for the record, I have absolute, total, 100% confidence that Histogen is NOT lying. I have spoken with them numerous times and these are well-intentioned people. But one thing is that they are using some different growth factors from the growth factors that Dr. Nigam is using so that could change the results although I think that with Dr. Nigam using growth factors in combo with cells that could perhaps solve the problem like I said.

Keep in mind that Histogen has demonstrated that it's best to get repeat injections so we should plan to go back and forth to India 5 or 6 times over a 6 month period for repeat injections.





Originally Posted by KO

Unless Histogen is flat out lying about their work, we should be able to replicate it to some extent, especially Dr Nigam, with his lab. He can culture neonatal foreskin fibroblasts to produce these growth factors. So yeah, IF histogen is not lying, we are close.

I am Indian myself, so going there is not a huge problem, my question is really, what stage is Dr Nigam in the development process and which protocol (growth factors/HM/DP culture) is most mature?





jarjarbinx is located in [NA] and he is available to meet: NO

drnigam

19.05.2013, 20:58

@ Noyznarcos

Stem Cell HM Result, 4 month@Dr. Nigam

Noyznarcos,
To get to MPB cure we need to approach it for multiple angles.
There are people who do not want to undergo FUT/FUE OR EVEN DOUBLING...
Regarding your question...
Since you want to take care of your problem now...with total success and safety..
The best option i have as on today is...
DONOR DOUBLING WITH INJECTIONS OF ACTIVATED STEMCELLS,INJECTIONS OF DP CELLS,INJECTION OF DERMAL PAPILLA CELLS...and if a patient is ready to visit again..you should also have dp culture and multiplied stemcells injection...

With this technique i am confident that an nw7 with poor donor can also be converted to nw2..with few visits..

Depending on what is your nw status..you will need to be at mumbai for 3 days to 5 days...and 1/2/3 visits.

You can follow the 3 threads, on forum,
with documentation of donor doubling
.i have posted one month result and will post second month result in next 15 days...

One case is of hair doubling of approx 5000grafts to 10000 grafts,and the other case we have at present done donor doubling of approx,4500plus grafts..
3rd case of creating 90 follicles from 23 follilces...

There were two papers presented by japanese guys, at the wchr congress, independently confirming that if a follilce is bisected and its upper half have atleast outer root sheath..it can generate its own dermal papilla,

and the other paper confirmed .that is,dp cells are injected under the bisected upper follicle ...a new dp is generated...


Originally Posted by Noyznarcos

Doctor Nigam that most lay users of this forum wants to see are pictures and certified independent safety. Stop.

The issues tecnicne dp cell, 3d culture spgeroidal for someone who is not a graduate student in biomedical engineering is how to speak Arabic.

Doctor avoids, please, talk about 100 different things you want to do in the future.

Many of us in these forums want something NOW to be able to enjoy life to 100%, and not to think about this problem.

Since you say that there are no problems with the doubling, and you can engage 20,000 uf in 1 year. Well Fixed an affordable price 10-12 K and begins to work.

How's that for a solution, the rest is just talk and campaign promises that we do not need.

I hope you understand my speech.

thanks




drnigam has 1 Personal Journal(s). Click here to view
drnigam is located in [NA] and he is available to meet: YES
email hairsite@aol.com to arrange a meeting.

TheThing

19.05.2013, 21:14

@ jarjarbinx

Stem Cell HM Result, 4 month@Dr. Nigam

Also, I don't think we should say anything outside of the Hairsite forums because we don't want a million people flying to India to get treatment from Dr. Nigam since that will create a waiting list to see him. We want to get all the Hairsite posters done first and then perhaps go on TV or something to let everyone see our results and recommend Dr. Nigam to the rest of the world after we are done getting our treatments and our hair has grown out so that we can show the world the great success if we can get this cured soon.]


Dr Nigam posts on several boards and I'm guessing he will share these pictures with the rest of them.




TheThing is located in [NA] and he is available to meet: NO

picaso

19.05.2013, 21:24

@ jarjarbinx

Stem Cell HM Result, 4 month@Dr. Nigam

jarjarbinx,

I am also willing to join you guys if and when this actually happens. I have great confidence in Dr Nigams, but think that a bit more tweaking is required before Dr. Nigams has it completely figured out. I am a NW6/7 so if this actually works, the results would be very evident on my head becuase I dont have diffuse thinning, I am completely bald on top so any results would have to show.

I would require a high artistic standard for my hairline, so just because Dr Nigams has the science figured out, we must also be careful that the techs that he has working with him are experienced in that regard. I don't think that we can just inject all these cells and the hairline will come out looking perfect. I think that it will require artistic ability to place grafts into the hairline via hair doubling or plucking... or even fue/bht. The nape hair tends to work very well for the hairline. Once the profile of the face looks good with the hairline, the rest doesn't matter as much.

Anyway, what do you guys think of starting a yahoo group or privae facebook group for those of us who are willing to go to Dr. Nigams? We can take a group trip, it would come out much cheaper, and maybe we can even start a fund or something so that out trip can be partly sponsored / subsidized and we will report back to everyone on our progress.




picaso is located in [NA] and he is available to meet: NO

jarjarbinx

19.05.2013, 22:03

@ TheThing

Stem Cell HM Result, 4 month@Dr. Nigam

Thing it would still be best if we here at Hairsite, and the posters at the other sites where Dr. Nigam is posting, do not say too much about Dr. Nigam's progress until we have all gotten to go and get Dr. Nigam's best treatment and recover our hair. Then I am sure it would be easy for us to a major national news story about Dr. Nigam's treatments if he wants us to. But in the meantime all of here at Hairsite, and the posters at the other sites where Dr. Nigam posts, we should all keep this quiet.




Also, I don't think we should say anything outside of the Hairsite forums because we don't want a million people flying to India to get treatment from Dr. Nigam since that will create a waiting list to see him. We want to get all the Hairsite posters done first and then perhaps go on TV or something to let everyone see our results and recommend Dr. Nigam to the rest of the world after we are done getting our treatments and our hair has grown out so that we can show the world the great success if we can get this cured soon.]

Originally Posted by TheThing


Dr Nigam posts on several boards and I'm guessing he will share these pictures with the rest of them.





jarjarbinx is located in [NA] and he is available to meet: NO

KO

19.05.2013, 22:05

@ drnigam

Stem Cell HM Result, 4 month@Dr. Nigam

Great stuff. I see your point now, the logic behind using treatments of DP+Ep+growth factors is to hit it from multiple angles.


When did you start using each of these? You have given us the impression that you recently started injecting patients with the above 3 therapies.




KO is located in [NA] and he is available to meet: NO

jarjarbinx

19.05.2013, 22:09

@ picaso

Stem Cell HM Result, 4 month@Dr. Nigam

If Dr. Nigam can restore our hair by way of cells and growth factors then you won't have to worry about transplanting follicles because the newly injected cells and growth factors will use the already existing follicles that you have in your scalp skin start producing hairs again and those follicles already situated to have the right tilt and spacing. In other words, if Dr. Nigam can cure hair loss using cells and growth factors then the new hair will grow out of your old follicles (which are lying there dormant) and those old follicles will produce hair growing out (articulating) the same direction and spacing that they used to before hair loss started. This is the advantage to a treatment that utilizes the hair follicles that you already have - such a treatment results in the new hairs growing out the same as they did before hair loss started since the new hairs would be growing from, and passing through, the old follicles.



Originally Posted by picaso

jarjarbinx,

I am also willing to join you guys if and when this actually happens. I have great confidence in Dr Nigams, but think that a bit more tweaking is required before Dr. Nigams has it completely figured out. I am a NW6/7 so if this actually works, the results would be very evident on my head becuase I dont have diffuse thinning, I am completely bald on top so any results would have to show.

I would require a high artistic standard for my hairline, so just because Dr Nigams has the science figured out, we must also be careful that the techs that he has working with him are experienced in that regard. I don't think that we can just inject all these cells and the hairline will come out looking perfect. I think that it will require artistic ability to place grafts into the hairline via hair doubling or plucking... or even fue/bht. The nape hair tends to work very well for the hairline. Once the profile of the face looks good with the hairline, the rest doesn't matter as much.

Anyway, what do you guys think of starting a yahoo group or privae facebook group for those of us who are willing to go to Dr. Nigams? We can take a group trip, it would come out much cheaper, and maybe we can even start a fund or something so that out trip can be partly sponsored / subsidized and we will report back to everyone on our progress.





jarjarbinx is located in [NA] and he is available to meet: NO

appleguy

19.05.2013, 23:07

@ jarjarbinx

Stem Cell HM Result, 4 month@Dr. Nigam

I'm wondering if those awakened follicles would still be at risk from future MPB. Would you then need to take finasteraide / minox to maintain?
I hope not...




appleguy is located in [NA] and he is available to meet: NO

RickH

19.05.2013, 23:37

@ drnigam

Stem Cell HM Result, 4 month@Dr. Nigam

Is it possible to know at this time whether the hair generated with this method is resistant to MPB? Or, should we expect that a patient will need periodic re-injections, just as a positive responder to finasteride or dutasteride will lose any hair they've regained if they stop taking that medication?

Also, how certain can one be that there is no cancer risk? Since this is new territory being explored, how is it possible to know what is around the next corner?




RickH is located in [NA] and he is available to meet: NO

jarjarbinx

19.05.2013, 23:50

@ appleguy

Stem Cell HM Result, 4 month@Dr. Nigam

I don't know. But I do know that if the treatment works I will do the whole treatment process again in 5 years if that is what I have to do to keep my hair. And if you decide not to get the treatment at all just because you will need to repeat the treatment process again in 5 years I want you to know that I will look after the women for you while you stay bald by choice;-).

So if the treatment works but you decide to stay bald anyway by choice then at least you won't have to worry about the women getting idle because I will keep them very VERY busy while you stay bald by choice.



Originally Posted by appleguy

I'm wondering if those awakened follicles would still be at risk from future MPB. Would you then need to take finasteraide / minox to maintain?
I hope not...





jarjarbinx is located in [NA] and he is available to meet: NO

jarjarbinx

19.05.2013, 23:52
(edited by jarjarbinx, 20.05.2013, 00:07)

@ RickH

Stem Cell HM Result, 4 month@Dr. Nigam

I don't know. Nobody knows. But if you would have to do treatment again in 5 years I suggest you do that or else I will look after the women for you while you stay bald by choice.




Originally Posted by RickH

Is it possible to know at this time whether the hair generated with this method is resistant to MPB? Or, should we expect that a patient will need periodic re-injections, just as a positive responder to finasteride or dutasteride will lose any hair they've regained if they stop taking that medication?

Also, how certain can one be that there is no cancer risk? Since this is new territory being explored, how is it possible to know what is around the next corner?





jarjarbinx is located in [NA] and he is available to meet: NO

KO

20.05.2013, 01:19

@ jarjarbinx

Stem Cell HM Result, 4 month@Dr. Nigam

My suspicion is that those follicles will be susceptible to AGA again, because nothing is really protecting them. But if the treatment works, it should still give hair for a few years.

As for the growth factors:

Wnt7a - this is required for hair inducing capability in DP cells.

KGF - this is a potent promoter of epithelial cell proliferation, and I suspect, this is what may be converting epithelial stem cells to progenitor cells. (BUT I could be wrong...)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1869891/

VEGF - No idea

Follistatin - No idea



It seems to me that HSC's goal is to promote conversion of stem cells to progenitor cells and DP proliferation...I can't think of any other way that this would grow hair.




KO is located in [NA] and he is available to meet: NO

Freddie555

20.05.2013, 01:23

@ drnigam

Stem Cell HM Result, 4 month@Dr. Nigam

As on today not all patients will be as lucky as this guy.


The result for this individual is reasonably good.

But the question is why are these good results not seen in other patients with stem cell HM?

Another thing I notice is that the patient looks young. This suggests stem cell HM is not necessarily creating new hair follicles but perhaps reviving existing follicles which are still hanging onto life.

If you can create hair in a slick bald patch on an old guy using stem cell HM, that wil be a great step forward.

It still feels like we are years away from a cell cure because nothing has been demonstrated to work conclusively on a consistent basis when it comes to follicular neogenesis.




Freddie555 is located in [NA] and he is available to meet: NO

---
"When true Hair Multiplication comes, it will arise out of the East." - John The Revelator, Feb. 18, 2001

KO

20.05.2013, 01:28

@ Freddie555

Stem Cell HM Result, 4 month@Dr. Nigam

^Yes, I think the most common effect is revitalization of existing follicles. This is confirmed by Ken Washenik who was saying that HM results look like great finasteride responders - the transition balding zone thickens up.


But a combination of this with DP cell injections, and growth factor injections could knock down more barriers - which I believe is Dr Nigam's idea.




KO is located in [NA] and he is available to meet: NO

jarjarbinx

20.05.2013, 01:32
(edited by jarjarbinx, 20.05.2013, 01:50)

@ KO

Stem Cell HM Result, 4 month@Dr. Nigam

We know that Histogen's growth factors are working for at least 2 or 3 years so far because the Histogen pilot study subjects have not lost their recovered hair and those test patients were given a single low-dose injection date.

That aside, if the multi-pronged approach we're discussing actually works, but the treatment is only good for 5 years, then we'll have to repeat the treatment process after 5 years or we'll lose our hair again. those will be our only two choices. It is what it is.



Originally Posted by KO

My suspicion is that those follicles will be susceptible to AGA again, because nothing is really protecting them. But if the treatment works, it should still give hair for a few years.

As for the growth factors:

Wnt7a - this is required for hair inducing capability in DP cells.

KGF - this is a potent promoter of epithelial cell proliferation, and I suspect, this is what may be converting epithelial stem cells to progenitor cells. (BUT I could be wrong...)
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1869891/

VEGF - No idea

Follistatin - No idea



It seems to me that HSC's goal is to promote conversion of stem cells to progenitor cells and DP proliferation...I can't think of any other way that this would grow hair.





jarjarbinx is located in [NA] and he is available to meet: NO

RickH

20.05.2013, 04:39
(edited by RickH, 20.05.2013, 05:06)

@ jarjarbinx

Stem Cell HM Result, 4 month@Dr. Nigam

Ah, now I see why people here dislike you, "JarJar."

First, I'm not bald.
Second, if I were cue-ball bald I still wouldn't be the least bit concerned that someone like you could take a woman from me.
Third, I wasn't talking to you. I was directing legitimate questions to Dr Nigam.




RickH is located in [NA] and he is available to meet: NO

jarjarbinx

20.05.2013, 05:05
(edited by jarjarbinx, 20.05.2013, 05:48)

@ RickH

Stem Cell HM Result, 4 month@Dr. Nigam

I don't care if "people here dislike" me. I have the best point in ALMOST every disagreement I get into. Occasionally I'm proved wrong but not very often. The last time I was proved wrong was when KO proved that Aderans actually has done repeat-treatment testing and I was arguing that Aderans has not done so. I was wrong then, but that was then and this is now.

You don't seem to appreciate that if we're able to get a treatment to give us our hair back, with the only downside being that we have to repeat the treatment once every 5 years, we would be lucky. We're at war with Mother Nature here. You might as well try to stop a tidal wave from coming ashore, or stop a volcano from erupting, or stop the earth from rotating on its' axis. The force we are up against is unimaginably powerful, and better men than us have had their entire lives ruined by baldness. Hippocrates, for example, became obsessed with his hair loss and spent his entire life trying unsuccessfully to regrow his lost hair.

It would be an historic monumental event if Dr. Nigam actually finds a way to consistently regrow a full head of hair on bald heads, but even then he wouldn't be able to say how long that new hair would last, or how often one would need re-treatment. The treatments he's investigating are truly cutting-edge and nobody would have the answers to your questions so soon.

I just read a story about two boys with the exact opposite condition from baldness - they have hair everywhere. They're billed as "wolf boys" in the circus they were raised in. People go to see them, stare at them, and talk about what freaks they are. They want a cure but they can't be cured for ANY amount of time, much less 5 years with continuing options to purchase more 5 year breaks from their disease.

There are cancer patients with days to live who would give an arm or a leg to get 5 years longer on earth with the option to purchase another 5 years after those 5 years run out. They can't have that deal.

We bald people have it bad for sure, but there are people who have it worse than us, and they have no hope at all. If you are able to completely reverse your baldness soon, with the only downside being that you have to be re-treated every 5 years, you should consider yourself lucky and blessed. There are a lot of people with other diseases who want for that kind of progress against the medical conditions they're battling against.






Originally Posted by RickH

Ah, now I see why people here dislike you, "JarJar."

First, I'm not bald.
Second, if I were cue-ball bald I still wouldn't be the least bit concerned that someone like you could take a woman from me. You wouldn't know what to do with a woman if you could get one.
Third, I wasn't talking to you. I was directing legitimate questions to Dr Nigam. So, get back to your internet porn and let the grown-ups talk.





jarjarbinx is located in [NA] and he is available to meet: NO

hairman2

20.05.2013, 07:41

@ jarjarbinx

Stem Cell HM Result, 4 month@Dr. Nigam

:rotfl:

I don't care if "people here dislike" me. I have the best point in ALMOST every disagreement I get into. Occasionally I'm proved wrong but not very often.





hairman2 is located in [NA] and he is available to meet: NO

jarjarbinx

20.05.2013, 07:54

@ hairman2

Stem Cell HM Result, 4 month@Dr. Nigam

Hairman's toppik before and after pics:

Before:

http://www.hairlosstalk.com/img/toppik-women-beforelg03.jpg

After:

http://www.hairlosstalk.com/img/toppik-women-afterlg03.jpg




jarjarbinx is located in [NA] and he is available to meet: NO

gettingthere

20.05.2013, 09:33

@ drnigam

Stem Cell HM Result, 4 month@Dr. Nigam

Dr. Nigam,

I read you are coming to San Francisco, I am from San Francisco and I can't really afford your procedure as a student but I am a diffusely thinner in his mid 20's and seem like I could be a really good candidate for your procedure and would be happy to take high quality before and after pictures for the hairsite users if you would be willing to perform the procedure on me. I don't want to sound like a pity case as everyone here struggles with hair loss but it has been especially difficult for me and I feel like it would help solidify the authenticity of your procedure to US forum users so it could be beneficial to all parties...

What does everyone think?




gettingthere is located in [NA] and he is available to meet: NO

hairman2

20.05.2013, 11:04

@ jarjarbinx

Stem Cell HM Result, 4 month@Dr. Nigam

once again jarjar you have the BEST point. Your intellect is so impressive.

Originally Posted by jarjarbinx

Hairman's toppik before and after pics:

Before:

http://www.hairlosstalk.com/img/toppik-women-beforelg03.jpg

After:

http://www.hairlosstalk.com/img/toppik-women-afterlg03.jpg





hairman2 is located in [NA] and he is available to meet: NO

KO

20.05.2013, 13:54

@ gettingthere

Stem Cell HM Result, 4 month@Dr. Nigam

What I think is you need to take finasteride first? Can you not tolerate the drug or something?




KO is located in [NA] and he is available to meet: NO

caddarik79

20.05.2013, 14:25

@ drnigam

Stem Cell HM Result, 4 month@Dr. Nigam

dear Dr Nigam,

Is that kind of treatment going to be OK for people who already got transplanted hair on top?




caddarik79 is located in [NA] and he is available to meet: NO

scarred5

20.05.2013, 16:20

@ caddarik79

Stem Cell HM Result, 4 month@Dr. Nigam

exactly what i was thinking, ive had alot and my donor is toast, but i feel alot of tiny stubble all over my scalp, im not on any dht inhibitors, i think all these injections would get them to grow, and id be willing to go to india, as ive been all over the world pretty much already trying to repair my head, but going every couple of months or whatever dr nigam is advocating would be difficult and expensive, as ive dropped a ton of hard earned cash already, hope dr nigam can give us some insight



scarred5 has 2 Personal Journal(s). Click here to view
scarred5 is located in [NA] and he is available to meet: NO

drnigam

20.05.2013, 18:42

@ caddarik79

Stem Cell HM Result, 4 month@Dr. Nigam

caddarik,
As explained in the other post..
The scalp who has undergone implantation and extraction of follicles will have microscarring..it is only at micro scarring they will not be any dormant telogen follicle..and there is no possibilty on the micro scar for de nove neofollicular formation..
But the rest of the normal scalp should fine...as any normal scalp...only lichen planus.burnt scar,autoimmune scar,psoriasis may have problem on the scarred area...


Originally Posted by caddarik79

dear Dr Nigam,

Is that kind of treatment going to be OK for people who already got transplanted hair on top?




drnigam has 1 Personal Journal(s). Click here to view
drnigam is located in [NA] and he is available to meet: YES
email hairsite@aol.com to arrange a meeting.

lalyric

20.05.2013, 18:50

@ drnigam

Stem Cell HM Result, 4 month@Dr. Nigam

scarred5 how many surgeries have you had?




lalyric is located in [NA] and he is available to meet: NO

lalyric

20.05.2013, 19:02
(edited by lalyric, 20.05.2013, 19:22)

@ caddarik79

Stem Cell HM Result, 4 month@Dr. Nigam

caddarik79 i think you be good the transplant hair dont fall out so the only thing you need is these multiply injections and you be right back to where you started before your hair started to fall out




lalyric is located in [NA] and he is available to meet: NO

scarred5

20.05.2013, 19:14

@ lalyric

Stem Cell HM Result, 4 month@Dr. Nigam

to many, but like i said i have tons of tiny hairs i can feel with the tip of my finger, was thinking bout trying dut, i still may but ive tried propecia for several yrs when i was younger, with no benefit, may still try this though



scarred5 has 2 Personal Journal(s). Click here to view
scarred5 is located in [NA] and he is available to meet: NO

jarjarbinx

20.05.2013, 21:20

@ hairman2

Stem Cell HM Result, 4 month@Dr. Nigam

I liked your before pic best Hairman so I think you should stop wasting money on toppik. The before pic produced a cute piteous look about you.



once again jarjar you have the BEST point. Your intellect is so impressive.

Originally Posted by jarjarbinx

Hairman's toppik before and after pics:

Before:

http://www.hairlosstalk.com/img/toppik-women-beforelg03.jpg

After:

http://www.hairlosstalk.com/img/toppik-women-afterlg03.jpg


Originally Posted by hairman2





jarjarbinx is located in [NA] and he is available to meet: NO

gettingthere

20.05.2013, 23:14

@ KO

Stem Cell HM Result, 4 month@Dr. Nigam

I'm on fin, been on it for several years now and it's maintained my hair for the most part, very little recession and not much thinning since but it's still thin I just have enough to use concealers.




gettingthere is located in [NA] and he is available to meet: NO

KO

20.05.2013, 23:41

@ scarred5

Stem Cell HM Result, 4 month@Dr. Nigam

If you did not get sides, you should take the drug, because the main benefit is slowing down hair loss...




KO is located in [NA] and he is available to meet: NO

scarred5

21.05.2013, 00:15

@ KO

Stem Cell HM Result, 4 month@Dr. Nigam

your absolutely right, maintaining or even slowing the progression should be the goal, but my hairloss stabilized @ 5a, and it has not progressed in over 10 yrs, like i said still may try this though



scarred5 has 2 Personal Journal(s). Click here to view
scarred5 is located in [NA] and he is available to meet: NO

RickH

21.05.2013, 04:40

@ jarjarbinx

Stem Cell HM Result, 4 month@Dr. Nigam

Again, I wasn't talking to you. However, I will respond to you.

Asking whether the treatment will have to be repeated periodically isn't a criticism of the treatment. It is simply a desire to get more details.

And asking about cancer concerns is obviously a valid question to any thinking person. There may be NO cancer concerns. I asked the doctor because I want to find that out. If there ARE cancer concerns, I doubt you will have a better chance to pick up my women from the cancer ward.




RickH is located in [NA] and he is available to meet: NO

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