Hair Multiplication & Stem Cells Hair Treatment

Your go-to repository for the latest in cell-based hair restoration news.  

Hair multiplication, hair cloning or cell-based hair technologies is the most anticipated research in hair restoration nowadays.  Get caught up quickly and effortlessly with the latest in minimally invasive hair technologies using our quick filters below. If you prefer to dive into a more involved discussion about the latest trends, visit our forum link below.

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25-Businesswire

⇒ Stemson, famous for its hair regeneration research based on induced pluripotent stem cells (iPSC), gains a complementary technology through an exclusive licensing agreement with Aderans. Aderans is the parent company of Bosley Medical and Hair Club with a vast distribution network in the United States. Under this agreement, Stemson will resume Aderans’ Phase 2 clinical stage cell therapy hair regeneration program and integrate the technology into its existing pipelines for non invasive cell based hair regeneration products.
⇒ comments

2 months
PR Newswire

⇒ PP405 is a topical molecule that is able to reactivate dormant hair follicle stem cells and stimulate new hair growth. The study is carried out by researchers at UCLA. PP405 works by inhibiting the mitochondrial pyruvate carrier (MPC) to specifically reactivate the dormant hair follicle stem cells. Phase 2 trial is expected to begin in mid 2024.
⇒ comments

3 months
NLM: Exp Dermatol

⇒ Research demonstrated that Exosomes promote the proliferation, viability and migration of senescent Dermal Papilla Cells (DPCs) while inhibiting cell death and may present new breakthrough in hair regeneration and prevention of hair loss. 

Exosomes treatment available at AlviArmani

4 months
Mallia

⇒ Mallia Therapeutics new development: sCD83, an immune-modulatory protein that binds directly to hair follicles, regulates T cells and induces hair growth.
⇒ comments

5 months
RPI.EDU

⇒ First time researchers used 3D printing technology to create new hair follicles.
⇒ Rensselaer Polytechnic created new hair follicles in lab-grown skin using 3D printing technology.
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6 months
Feller Medical

⇒ Feller-Bloxham Verteporfin hair regeneration experiment month 2 & 3 update; possibility of unlimited donor follicles.
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6 months
Stemson

⇒ Stemson’s induced Pluripotent Stem Cells (iPCS) Oct 2023 update: net new supply of hair follicles latest roadmap timeline.
⇒ Research article: derivation of hair inducing pluripotent stem cells.
⇒ comments

7 months

10 months
NLM: Arch Dermatol Res

⇒ Stromal Vascular Fraction cells (SVFs) are adipose tissue stem cells consisting of several types of cells, including Adipose Derivate Stem Cells (ADSCs). Study involving 30 test subjects with pattern baldness received a single injection of autologous SVF injection. Over a 6-month period, test patients noticed an increase in hair diameter by over 50% and an increase in hair count per sq cm by over 16%. In addition, terminal (anagen) to vellus (telogen) increased by about 5%. 

11 months
Wiley: J of Cosmetic Derm

⇒ Applications of exosomes isolated from ADSCs (ADSC-Exo) and DPCs have shown early promising results in preclinical studies corroborated by results obtained from different model systems. Topical ADSC-Exo has been tried successfully in 39 androgenetic alopecia patients demonstrating significant increases in hair density and thickness.

available at AlviArmani

11 months
Amplifica

⇒ Amplifica started human hair regrowth trial using Senescent cells.
⇒ comments

11 months
26-NBCNews

⇒ Skin moles led to new research in cell based hair regeneration research. Maksim Plikus, co-founder of Amplica and also professor at UC, Irvine, demonstrated that a molecule called osteopontin which is particularly prominent in hairy skin moles could activate dormant hair follicle stem cells and stimulate hair regrowth. Human trials have been planned to further research and develop this compound into commercially viable treatment that can be administered via scalp injections to promote hair growth.

11 months
SciTechDaily

⇒ Senescent pigment cells stimulate hair growth by producing a signaling molecule called Osteopontin which interacts with a receptor molecule called CD44 to activate hair stem cells for robust growth.
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11 months
Nature

⇒ Researchers at University of California, Irvine discovered that Senescent cells can activate robust hair growth.
⇒ Senescent cells found to promote robust hair growth.
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11 months
Dr A’s clinic

⇒ Dr Arvind’s new gene therapy hair regeneration hack.
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12 months
Niostem

⇒ Niostem hair regrowth wearable device using hair stem cells reactivation technology (SCRT).
⇒ Niostem Indiegogo funding campaign.
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1 year
NIH: various

⇒ Comprehensive review of different types of stem cells for treating male and female hair loss. This meta review covers 15 studies involving a total of 653 participants. One of the 15 studies (Gentile et al) reported mean hair count increase of 18 times higher than the control group.

1 year
IB Times; Tech Times

⇒ Niostem introduces first ever wearable device to stimulate hair follicle stem cells using low level electrical current.
⇒ How Niostem works to regenerate hair growth.
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1 year
AIS

⇒ Best illustration on how Stemson’s induced Pluripotent Stem Cells (iPCS) generate net new hair follicles.
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2 years
NLM: Stem Cell Res Ther

⇒ Study using Stromal Vascular Fraction (SVF) cells isolated from fat as a hair regeneration therapy for patients with pattern hair loss or androgenetic alopecia. Total of 9 patients (4 men; 5 women) were involved in the study using a single injection of autologous SVF. Study concluded significant improvement in hair density and keratin level 6-month after one single injection.

3 years
Stanford Med

⇒ Stanford University researchers discovered scarless healing and possibility of hair follicles regeneration with Verteporfin. 
⇒ comments

3 years
NIH: Int J Mol Sci

⇒ Study involving 69 men with androgenetic alopecia or pattern baldness shows that Platelet Rich Plasma (PRP) is more effective in promoting hair growth than topical Minoxidil alone. After PRP hair therapy, there was a significant increase in β-catenin and CD34 expression as well as increase in Ki67+ index.

available at AlviArmani

4 years
Science Advances

⇒ Study showed that dermal Exosomes containting miR-218-5p plays a crucial role in exosome-mediated hair regrowth by regulating Beta-Catenin signaling.

available at AlviArmani

4 years
NLM – J Cosmet Dermatol

⇒ Combination therapy using both Stromal Vascular Fraction (SVF) and Platelet Rich Plasma (PRP) significantly improved hair regeneration and reversed effects of hair loss or androgenetic alopecia as compared to mono PRP therapy alone. Mean hair density increase in the SVF-PRP dual therapy group was over 50% compared to only 21% in the PRP mono therapy group. 

4 years
NIH: Aesthetic Plast Surg

⇒ Meta review of 11 studies show that Platelet Rich Plasma (PRP) is effective for treating male and female pattern hair loss. The review involved 11 studies covering 262 participants and concluded that a significant improvement with a mean difference of 38 hairs per cm2 increase in hair count compared to the control group.

available at AlviArmani

5 years
NIH: J Cosmet Dermatol

⇒ Review of six studies involving 177 test subjects confirm the effectiveness of Platelet Rich Plasma (PRP) in promoting hair growth for androgenetic alopecia patients. A statistically significant improvement in hair count (mean difference of 17.9) and hair thickness were observed in the pooled studies. 

available at AlviArmani

7 years
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